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IL-1 beta antibody

IL1B Reactivity: Sheep, Cow, Goat FACS, EIA, IHC (fro) Host: Mouse Monoclonal 1D4 unconjugated
Catalog No. ABIN120889
  • Target See all IL-1 beta (IL1B) Antibodies
    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
    Reactivity
    • 123
    • 87
    • 43
    • 27
    • 24
    • 13
    • 8
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Sheep, Cow, Goat
    Host
    • 175
    • 63
    • 6
    • 6
    • 4
    • 2
    • 1
    Mouse
    Clonality
    • 181
    • 74
    • 1
    Monoclonal
    Conjugate
    • 135
    • 40
    • 23
    • 10
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This IL-1 beta antibody is un-conjugated
    Application
    • 184
    • 107
    • 90
    • 46
    • 42
    • 39
    • 28
    • 17
    • 17
    • 15
    • 14
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    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Purification
    Purified
    Immunogen
    Recombinant ovine IL-1 Beta
    Clone
    1D4
    Isotype
    IgG1
    Top Product
    Discover our top product IL1B Primary Antibody
  • Application Notes
    ELISA: 5 μg/mL as coating antibody. Flow Cytometry: 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunohistochemistry on frozen sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.09 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.
    Expiry Date
    12 months
  • Target
    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
    Alternative Name
    Interleukin-1 beta / IL-1B (IL1B Products)
    Synonyms
    IL-1 antibody, IL1-BETA antibody, IL1F2 antibody, IL-1BETA antibody, IL1beta antibody, il1-b antibody, zgc:111873 antibody, IL-1B antibody, IL-1beta antibody, Il-1b antibody, IL1B antibody, IL-1 beta antibody, IL-1b antibody, interleukin 1 beta antibody, interleukin 1, beta antibody, IL1B antibody, il1b antibody, Il1b antibody
    Background
    Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25 % homology in their amino acid sequence.Synonyms: Catabolin, IL-1 beta, IL1 beta, IL1B, IL1F2
    Pathways
    NF-kappaB Signaling, Interferon-gamma Pathway, TLR Signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
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