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Acetylcholinesterase (AChE) antibody
| Antigen | Acetylcholinesterase (AChE) |
| Synonyms |
YT, ARACHE, N-ACHE, mE1a, mE1b, mE1c, mE1d, mE1e, mE1d', mE1c-long, ACE, AChE, AcChE, CHE, DmAChE, FBgn0000024, dAChE, l(3)26, l(3)87Ed, DmelCG17907, CG17907, zgc:92550, ACHE, Ache, GB14873, dsim_GLEA ...
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| Clonality | Monoclonal (HR2) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Cow (Bovine), Cat (Feline), Guinea Pig, Human, Rabbit |
| Application |
Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Immunoprecipitation (IP)
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| Catalog no. | ABIN121002 |
| Quantity | 0.2 ml |
| Price | 420.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Alternative name | Acetylcholinesterase |
| Swiss-Prot | P22303 |
| Immunogen | Purified human cerebellar acetylcholinesterase |
| Format | Ascites |
| Isotype | IgG2b (Matching secondary antibodies) |
| Clone | HR2 |
| Description | Cholinergic neurotransmission occurs in motor, autonomic and central nervous synapses and requires very rapid inactivation of its transmitter, acetylcholine (ACh). Acetylcholinesterase (AChE) rapidly hydrolyzes ACh to acetate and choline, thereby inactivating it. AChE is found in the neuromuscular junction anchored to the basal lamina which runs between the nerve terminal and muscle membrane. AChE is also found outside the nervous and neuromuscular system in blood, lymph, germ and liver cells suggesting a role for AChE not related to cholinergic transmission. Another less specific cholinesterase, butyrylcholinesterase (BChE), seems to contribute to the regulation of the ACh concentration in the synaptic cleft. |
| Specificity | This antibody detects acetylcholinesterase (AChE) from human, rabbit, guinea pig, bovine and cat tissues. This antibody does not detect butyrylcholinesterase (BChE). |
| Synonyms | YT, ARACHE, N-ACHE, mE1a, mE1b, mE1c, mE1d, mE1e, mE1d', mE1c-long, ACE, AChE, AcChE, CHE, DmAChE, FBgn0000024, dAChE, l(3)26, l(3)87Ed, DmelCG17907, CG17907, zgc:92550, ACHE, Ache, GB14873, dsim_GLEANR_4292, Dsim\GD20515, GD20515, arache, n-ache, ache |
Application Details
| Application Notes | Immunohistochemistry on frozen sections: 1/50, staining of AChE in human brain samples with ABIN121002 results in staining of nerve fibers and terminals. Immunoprecipitation. ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
| Buffer | PBS containing 0.05% sodium azide as preservative. |
| Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf Life: one year from despatch. |
| Research Area | Neurology, Neurotransmitters |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Acetylcholinesterase (AChE)", type "Antibodies"
| Hosts | Rabbit (18), Goat (13), Mouse (11), Sheep (2) |
| Reactivities | Human (24), Rat (Rattus) (7), Cow (Bovine) (6), Mouse (Murine) (4), Cat (Feline) (2), Rabbit (2), Electric eel (Electrophorus electricus) (1), Fish (1), Guinea Pig (1), Sheep (Ovine) (1) |
| Applications | Western Blotting (WB) (30), Enzyme Immunoassay (EIA) (17), ELISA (13), Immunoprecipitation (IP) (11), Immunofluorescence (IF) (6), Immunohistochemistry (IHC) (6), Dot Blot (Dot) (4), Immunohistochemistry (Frozen Sections) (IHC (fro)) (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunodiffusion (ID) (3), Radioimmunoassay (RIA) (3), ELISA (Detection) (2), Immunocytochemistry (ICC) (1) |
| Conjugates | Biotin (3), HRP (2) |
| Epitopes | C-Term (3), N-Term (3) |
