LYVE1 antibody (AA 25-235)

Catalog No. ABIN121151

Product Details anti-LYVE1 Antibody

Target: LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

Binding Specificity: AA 25-235

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LYVE1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human LYVE-1 (25-235 aa) purified from E. coli

Clone: 4G1

Isotype: IgG2b

Application Details

Application Notes: ELISA. Western blot (is 1:500 - 1:1,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.01 % Sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for LYVE1

Target: LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

Alternative Name: LYVE-1 (LYVE1 Products)

Synonyms: LYVE1 antibody, XLKD1 antibody, CRSBP-1 antibody, HAR antibody, LYVE-1 antibody, 1200012G08Rik antibody, Crsbp-1 antibody, Lyve-1 antibody, Xlkd1 antibody, lymphatic vessel endothelial hyaluronic receptor 1a antibody, lymphatic vessel endothelial hyaluronan receptor 1 antibody, lyve1a antibody, LYVE1 antibody, Lyve1 antibody

Background: Lymphatic vascular endothelial hyaluronan receptor-1(LYVE-1), a selective marker of the lymphatic endothelium, is a surface endocytic receptor for hyaluronan (HA), which is an extracellular glycosaminoglycan involved in cell adhesion and migration. HA is widely expressed on leukocytes, dendritic cells, and tumor cell, and is identified by searching expressed sequence tag (EST) databases for sequences homologous (41 % ) with the metastasis related CD44 Molecules.Synonyms: CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, LYVE1, Lymphatic vessel endothelial hyaluronic acid receptor 1, XLKD1

UniProt: Q9Y5Y7

Pathways: Glycosaminoglycan Metabolic Process