Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) antibody

Details for Product No. ABIN121252
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Antigen
Reactivity
Human, Mouse (Murine)
(255), (57), (53), (4), (2), (2), (2), (2), (2), (1)
Host
Mouse
(214), (45), (3), (2)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(10), (9), (9), (6), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4)
Application
Western Blotting (WB)
(197), (110), (57), (50), (36), (31), (13), (6), (6), (3), (2), (1), (1)
Pubmed 8 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Discontinued
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Immunogen His-tagged full-length human IKK3/IKKg protein
Clone 72C627
Isotype IgG1
Purification Protein G chromatography
Alternative Name NEMO / IKBKG (IKBKG Antibody Abstract)
UniProt Q9Y6K9
Application Notes Western blot analysis: 2.0 ug/ml, positive control: Jurkat or NIH 3T3 (a 48 kDa band is observed). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.05 % BSA and 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
Supplier Images
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) antibody Western blot analysis of 30 ug of total cell lysate from Jurkat (lane 1) and NIH-3T3 ...
General Harhaj, Sun: "IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein." in: The Journal of biological chemistry, Vol. 274, Issue 33, pp. 22911-4, 1999 (PubMed).

Jin, Giordano, Kibler et al.: "Role of adapter function in oncoprotein-mediated activation of NF-kappaB. Human T-cell leukemia virus type I Tax interacts directly with IkappaB kinase gamma." in: The Journal of biological chemistry, Vol. 274, Issue 25, pp. 17402-5, 1999 (PubMed).

Yamaoka, Courtois, Bessia et al.: "Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation." in: Cell, Vol. 93, Issue 7, pp. 1231-40, 1998 (PubMed).

Mercurio, Zhu, Murray et al.: "IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation." in: Science (New York, N.Y.), Vol. 278, Issue 5339, pp. 860-6, 1997 (PubMed).

Verma, Stevenson: "IkappaB kinase: beginning, not the end." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 22, pp. 11758-60, 1997 (PubMed).

DiDonato, Hayakawa, Rothwarf et al.: "A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB." in: Nature, Vol. 388, Issue 6642, pp. 548-54, 1997 (PubMed).

Régnier, Song, Gao et al.: "Identification and characterization of an IkappaB kinase." in: Cell, Vol. 90, Issue 2, pp. 373-83, 1997 (PubMed).

Verma, Stevenson, Schwarz et al.: "Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation." in: Genes & development, Vol. 9, Issue 22, pp. 2723-35, 1995 (PubMed).

Validation Images
Catalog No. ABIN121252
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