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Details for Product No. ABIN121273

MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1) (AA 387-403) antibody

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Antigen
Synonyms COCA2, FCC2, HNPCC, HNPCC2, hMLH1, 1110035C23Rik, AI317206, AI325952, AI561766, CG11482, Dmel\\CG11482, dmlh-1, dmlh1, zgc:66301, MLH1, LOC100232198
Epitope
»Alternatives AA 387-403
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN121273
Quantity 0.1 mg
Price
445.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Synthetic peptide corresponding to amino acids 387-403 of human MLH1 GenBank no. NP_000240.1. AA Sequence:DSREQKLDAFLQPLSKP
Clone 164C819
Isotype IgG
Purification Protein G Chromatography.
Alternative Name MLH1
Background Human Mut L Homologue (MLH1) is homologous to the bacterial DNA mismatch repair Mult L gene. Mutations in the hMLH1 gene is associated with hereditary non-polyposis colon cancer and various other cancers. Alternate Names: MutL protein homolog 1, HNPCC.
UniProt P40692
Research Area Cancer, DNA/RNA
Application Notes Western blot: 2 - 3 ug/ml. In Molt-4, a 83 kDa band is observed. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.05% BSA as stabilizer and 0.05% Sodium Azide as preservative.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
Bronner, Baker, Morrison et al.: "Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer." in: Nature, Vol. 368, Issue 6468, pp. 258-61, 1994 (PubMed).

Alternatives for antigen "MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)", type "Antibodies"
Hosts (64), (36)
Reactivities (94), (36), (31), (15), (13), (8), (6), (1), (1), (1), (1), (1)
Applications (59), (32), (25), (15), (10), (9), (9), (8), (8), (6), (5), (3), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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