Presenilin 1 (PSEN1) (N-Term), (AA 14-33) antibody

Details for Product No. ABIN121548
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms pre1, psen, zfPS1, zf-PS1, ad3, fad, ps1, s182, X-PS-beta, X-PS-alpha, AD3, FAD, PS-1, PS1, S182, Ad3h
Epitope
N-Term, AA 14-33
(37), (21), (6), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(171), (79), (54), (36), (36), (36), (24), (24), (4), (1)
Host
Goat
(127), (36), (11), (2), (2), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(6), (6), (4), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(126), (74), (59), (40), (30), (15), (14), (6), (5), (1), (1)
Pubmed 4 references available
Quantity 0.1 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN121548
467.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen N-terminus peptide (amino acids 14-33) of presenilin-1
Purification Serum
Alternative Name Presenilin-1
Background Presenilin-1 is a protein that has been linked with an early onset form on Alzheimers disease. Presenilin-1 is a membrane protein whose function is, as yet, undetermined.
UniProt P49768
Research Area Alzheimer's Disease
Application Notes ELISA. Western Blot. Immunohistochemistry on frozen sections: 1:1000. Immunohistochemistry on paraffin sections: 1:100, this product does not require protein digestion pre-treatment of paraffin sections, this product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Recommended Positive Control: Brain. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer Containing 0.09% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
General Sherrington, Rogaev, Liang et al.: "Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease." in: Nature, Vol. 375, Issue 6534, pp. 754-60, 1995 (PubMed).

Kovacs, Fausett, Page et al.: "Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells." in: Nature medicine, Vol. 2, Issue 2, pp. 224-9, 1996 (PubMed).

Uchihara, el Hachimi, Duyckaerts et al.: "Widespread immunoreactivity of presenilin in neurons of normal and Alzheimer's disease brains: double-labeling immunohistochemical study." in: Acta neuropathologica, Vol. 92, Issue 4, pp. 325-30, 1997 (PubMed).

Murphy, Forno, Ellis et al.: "Antibodies to presenilin proteins detect neurofibrillary tangles in Alzheimer's disease." in: The American journal of pathology, Vol. 149, Issue 6, pp. 1839-46, 1997 (PubMed).

Validation Images
Did you look for something else?
back to top