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DFFA antibody (DNA Fragmentation Factor, 45kDa, alpha Polypeptide) (AA 312-331)

Details for Product anti-DFFA Antibody No. ABIN121557, Supplier: Login to see New
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Antigen
Synonyms DFFA, DFF-45, DFF1, ICAD, A330085O09Rik, DFF35, Dff45, ICAD-L, ICAD-S
Alternatives
Epitope
AA 312-331, C-Term
(40), (34), (20), (16), (14), (13), (12), (10), (5), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine)
(172), (77), (32), (1), (1)
Host
Rabbit
(198), (37), (2)
Clonality
Polyclonal
Conjugate
This DFFA antibody is un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(193), (73), (41), (31), (28), (23), (15), (11), (6), (4), (4), (3), (2), (1), (1), (1)
Pubmed 2 references available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Synthetic peptide corresponding to amino acids 312-331 of mouse ICAD
Specificity This antibody reacts to ICAD.
Purification Affinity chromatography
Alternative Name DFFA / ICAD (DFFA Antibody Abstract)
Background ICAD (Inhibitor of Caspase-Activated DNase) is the murine homologue of human DFF-45. ICAD is cleaved by Caspase-3, releasing CAD which eventually causes degradation of DNA in the nucleus.Synonyms: DFF-45, DFF1, DFF45, DNA fragmentation factor 45 kDa subunit, DNA fragmentation factor subunit alpha, Inhibitor of CAD
UniProt O54786
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis
Application Notes Western Blot: 1/500 - 1/1000, this antibody recognises a 45 kD band in Western blots.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS containing 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
Expiry Date 12 months
Background publications Enari, Sakahira, Yokoyama et al.: "A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD." in: Nature, Vol. 391, Issue 6662, pp. 43-50, 1998 (PubMed).

Wyllie: "Apoptosis. An endonuclease at last." in: Nature, Vol. 391, Issue 6662, pp. 20-1, 1998 (PubMed).

Catalog No. ABIN121557
$357.50
Plus shipping costs $45.00

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