8-Hydroxy-Guanosine (8-OHG) antibody

Antigen: 8-Hydroxy-Guanosine (8-OHG)

Clonality: Polyclonal

Host: Goat

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN121590

Additional Information

Immunogen: 8-Hydroxyguanosine - conjugate

Format: Serum

Description: Alternate Names: 8OHG.

Specificity: ABIN121590 recognises 8-hydroxyguanosine (8-OG), a modified base which occurs in DNA as a result of oxidative stress. 8-hydroxy-2'-deoxyguanosine (8-OHdG) has become a sensitive marker of oxidative damage in cellular DNA and has been reported to be excreted in the urine. Levels of 8-OHdG have been shown to increase on exposure to ionizing radiation and tobacco smoke. ABIN121590 cross reacts completely with 8-OHdG. This antibody does not cross react with other naturally occuring nucleotides.

Application Details

Application Notes: ELISA (1:100,000 - 1:250,000). Immunohistochemistry on paraffin embedded tissues (1:200). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Buffer: This antibody is supplied as liquid serum containing 0.09% sodium azide as as preservative.

Storage: Store the antibody undiluted at 2-8°C for one month or at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.

Restrictions: For Research Use only