SMAD, Mothers Against DPP Homolog 2 (SMAD2) antibody

Details for Product No. ABIN121675
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Antigen
Synonyms jv18, Xmad2, madh2, madr2, XSmad2, hmad-2, hsmad2, jv18-1, smad-2, fj43c06, wu:fj43c06, JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD2, 7120426M23Rik, Madh2, Madr2, Smad-2, mMad2
Reactivity
Human
(352), (197), (190), (79), (75), (65), (13), (3), (1), (1), (1), (1)
Host
Goat
(313), (37), (9)
Clonality
Polyclonal
Conjugate
Un-conjugated
(12), (10), (10), (6), (6), (6), (6), (6), (6), (6), (6), (4), (4), (4), (2)
Application
Western Blotting (WB)
(279), (144), (75), (65), (60), (52), (33), (18), (13), (9), (7), (6), (6), (2), (1), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

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Catalog No. ABIN121675
610.50 $
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  • +1 404 474 4654
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Immunogen Synthetic peptide SEIWGLSTPNTID derived from MADH2 protein sequence
Purification Affinity chromatography
Alternative Name SMAD2
Background This protein is a transcriptional modulator activated by TGF beta and may act as a tumour suppressor in colorectal carcinoma. It is found at high levels in skeletal muscle, heart and placenta. MADH2 exists in isoforms, a predominant long form and a short form missing the 30 amino acid exon 3. The short form shows DNA binding and higher transcriptional activation activity.Synonyms: JV18-1, MAD homolog 2, MADH2, MADR2, Mad-related protein 2, Mothers against DPP homolog 2, Mothers against decapentaplegic homolog 2, SMAD 2, SMAD family member 2, SMAD-2
Research Area Signaling, Transcription Factors
Application Notes Western Blot: 1/200 - 1/500, this antibody detects bands of approximately 45 kDa and 55 kDa in HeLa cell lysates, a minimum incubation time of 1 hour is recommended with this antibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer TRIS buffered saline pH 7.3 containing 0.02 % Sodium Azide and 0.5 % Bovine Serum Albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
Expiry Date 12 months
General Eppert, Scherer, Ozcelik et al.: "MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma." in: Cell, Vol. 86, Issue 4, pp. 543-52, 1996 (PubMed).

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