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s100 antibody (S100 Calcium Binding Protein A1)

Details for Product anti-S100A1 Antibody No. ABIN121826, Supplier: Login to see New
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Synonyms S100a1, S100A1, DKFZp468K0511, S100, S100-alpha, S100A, AI266795, S100a, NEF, S100-B, S100beta
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
(230), (99), (70), (64), (13), (10), (2), (1), (1), (1)
(169), (124), (10), (2), (1)
This s100 antibody is un-conjugated
(14), (13), (7), (5), (5), (5), (1)
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(167), (132), (115), (93), (37), (26), (19), (14), (10), (7), (5), (4), (3), (1), (1), (1), (1)
Pubmed 3 references available
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Quantity 1 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Bovine brain S-100
Specificity This antibody reacts with S-100 A and S-100 B. This protein is present in brain glial cells and in ependymal cells. This antibody also stains Schwann cells of the peripheral nervous system.
Characteristics Synonyms: S100-A1, S100A, S100 alpha, S100 calcium-binding protein A1, S-100 protein subunitalpha, S-100 protein alpha chain
Purification Ammonium Sulphate Precipitation
Alternative Name S100A1 (S100A1 Antibody Abstract)
Background Among tumours of the human central and peripheral nervous systems, schwannomas, ependymomas and astrogliomas of different stages, including glioblastomas show positive reactions. S100 can be detected in almost all benign naevi and malignant melanocytic tumours of the skin, and in Langerhans cells in the skin.Synonyms: S-100 protein alpha chain, S-100 protein subunit alpha, S100 alpha, S100 calcium-binding protein A1, S100-A1, S100A
Gene ID 528735
UniProt P02639
Application Notes Immunohistochemistry on Frozen Sections: 1/10-1/40. Immunohistochemistry on Paraffin Sections: 1/10-1/40. This product does not require protein digestion pretreatment of paraffin sections. Thisproduct does not require antigen retrieval using heat treatment prior to staining of paraffinsections. Recommended Positive Control: Brain, skin or Human melanoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-s100 antibody (S100 Calcium Binding Protein A1) (ABIN121826) S-100 – ABIN121826 - Human melanoma. Formalin fixed, paraffin processed tissue.
Background publications Kindblom, Lodding, Rosengren et al.: "S-100 protein in melanocytic tumors. An immunohistochemical investigation of benign and malignant melanocytic tumors and metastases of malignant melanoma and a characterization of the antigen in ..." in: Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology, Vol. 92, Issue 4, pp. 219-30, 1984 (PubMed).

Lauriola, Michetti, Sentinelli et al.: "Detection of S-100 labelled cells in nasopharyngeal carcinoma." in: Journal of clinical pathology, Vol. 37, Issue 11, pp. 1235-8, 1985 (PubMed).

Moore: "A soluble protein characteristic of the nervous system." in: Biochemical and biophysical research communications, Vol. 19, Issue 6, pp. 739-44, 1970 (PubMed).

Catalog No. ABIN121826
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