Chemokine (C-C Motif) Receptor 9 (CCR9) (C-Term) antibody

Antigen: Chemokine (C-C Motif) Receptor 9 (CCR9)

Synonyms: GPR28, CDw199, GPR-9-6, D6, hD6, CCR9, CCR10, CMKBR9, MGC126678, MGC138250

Epitope: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus)

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN121959

Additional Information

Alternative name: CDw199 / CCR9 (C-term)

Swiss-Prot: P51686

Immunogen: Synthetic peptide - KLH conjugated.

Description: CCR9, a chemokine receptor, is expressed in thymocytes and T lymphocytes from the small intestine and colon but not in lymphocytes from tonsils, lung, inflamed liver, normal or inflamed skin, inflamed synovium and synovial fluid, breast milk, and seminal fluid Kunkel et al., 2000). CCR9 is not detected in natural killer cells, monocytes, eosinophils, basophils, and neutrophils. CCR9 binds TECK (thymus-expressed chemokine), a CC chemokine expressed in thymus and small intestine. TECK chemoattracts dendritic cells, thymocytes, and activated macrophages. Alternate Names: CDW199, CMKBR9, g protein-coupled receptor gpr-9-6, gpr-9-6.

Specificity: Reacts with Chemokine Receptor 9 (.The immunizing peptide shows 100% identity / similarity with mouse and rat

Application Details

Application Notes: Immunohistochemistry on paraffin embedded sections: 2-4 ug/ml. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Concentration: 1 mg/ml

Buffer: PBS, pH 7.7, containing 0.01% sodium azide

Storage: Store the antibody at 2-8°C for one month or at -70°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.

Research Area: Chemokines, Receptors

Restrictions: For Research Use only

Images

Staining of human choroid plexus using ABIN121977