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Chemokine (C-C Motif) Receptor 8 (CCR8) antibody
| Antigen | Chemokine (C-C Motif) Receptor 8 (CCR8) |
| Synonyms | CY6, TER1, CKRL1, CDw198, CKR-L1, CMKBR8, CMKBRL2, GPR-CY6, MGC129966, MGC129973 |
| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
|
| Catalog no. | ABIN122025 |
| Quantity | 50 µg (1 mg/ml) (Variants) |
| Price | 430.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Alternative name | CDw198 / CCR8 |
| Swiss-Prot | P51685 |
| Immunogen | Synthetic peptide - KLH conjugated |
| Description | CCR8, a Chemokine Receptor, binds the CC-chemokine I-309, which is secreted by umbilical vein endothelial cells. CCR8 also binds viral monocyte inflammatory protein-I (vMIP-I), which is induced by Kaposi sarcoma-related human herpesvirus-8. CCR8 induces endothelial chemotaxis and may function as an HIV-1 co-receptor on primary human cells, contributing to HIV-1-induced thymic pathogenesis (Lee et al., 2000). Alternate Names: CDW198, CKR-L1, CKRL1, CMKBR8, CMKBRL2, CY6, GPRCY6, MGC129966, MGC129973, TER1, chemokine c-c motif receptor 8, chemokine c-c receptor-like 2, chemr1, ckr-l1. |
| Specificity | Reacts with C-C Chemokine Receptor 8 (.The immunizing peptide shows 47 % identity (65 % similarity) with mouse |
Application Details
| Application Notes | Immunohistochemistry with formalin fixed paraffin embedded tissues: 3-8 ug/ml Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. |
| Concentration | 1 mg/ml |
| Buffer | PBS, pH 7.7, containing 0.01% sodium azide |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -70°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch. |
| Research Area | Chemokines, Receptors |
| Restrictions | For Research Use only |
Images
| Immunohistochemical staining of Tonsil (Germinal Center) using anti- CCR8 antibody ABIN122025 |
Alternatives
Alternatives for antigen "Chemokine (C-C Motif) Receptor 8 (CCR8)", type "Antibodies"
| Hosts | Rabbit (6) |
| Reactivities | Human (6), Mouse (Murine) (1) |
| Applications | Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Western Blotting (WB) (3) |
| Epitopes | AA 183-201 (2) |
