G Protein-Coupled Bile Acid Receptor 1 (GPBAR1) (C-Term) antibody

Antigen: G Protein-Coupled Bile Acid Receptor 1 (GPBAR1)

Synonyms: BG37, GPCR, TGR5, M-BAR, GPCR19, GPR131, MGC40597, GPBAR1, MGC152072, Tgr5, MGC84403, Gpbar1

Epitope: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN122091

Additional Information

Alternative name: GPBAR1 / TGR5 (C-term)

Swiss-Prot: Q8TDU6

Immunogen: Synthetic peptide - KLH conjugated

Description: BG37/TGR5 is the first Bile Acid GPCR to be identified. BG37/TGR5 expression has been reported in a wide variety of tissues, especially placenta, spleen, and monocyte/macrophages. ESTs have been isolated from blood, breast, and skin libraries. Alternate Names: GPBAR1, GPCR, GPR131, HBG37, HGPCR19, M-BAR, G-Protein Coupled Bile Acid Receptor BG37, Membrane-type bile acid receptor, tgr5.

Specificity: Detects G Protein-Coupled Receptor (.The immunizing peptide shows 74 % identity (100 % similarity) with mouse and 68 % identity (73 % similarity) with rat

Application Details

Application Notes: Immunohistochemistry on paraffin embedded sections: 6-16 ug/ml Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Concentration: 1 mg/ml

Buffer: PBS, pH 7.7, containing 0.01% sodium azide

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -70°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.

Restrictions: For Research Use only

Images

Immunohistochemical staining of Placenta using anti- GPBAR1 antibody ABIN122091