G Protein-Coupled Receptor 119 (GPR119) antibody

Antigen: G Protein-Coupled Receptor 119 (GPR119)

Synonyms: GPCR2, hGPCR2, MGC119957, GPR119

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN122117

Additional Information

Alternative name: GPR119

Swiss-Prot: Q8TDV5

Immunogen: Synthetic peptide - KLH conjugated

Description: GPR119, a Lysophospholipid/Lysosphingolipid Receptor, has been shown to affect insulin secretion from pancreatic beta cells. Alternate Names: HGPCR2, MGC119957, GPCR2, gpr119.

Specificity: This antibody reacts with G Protein-Coupled Receptor GPR119 (family: GPCR, subfamily: Lysophospholipid/Lysosphingolipid).The immunizing peptide shows 60 % identity (85 % similarity) with mouse and 60 % identity (70 % similarity) with rat

Application Details

Application Notes: Immunohistochemistry with formalin fixed paraffin embedded tissues: 7-14 ug/ml Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Concentration: 1.0 mg/ml

Buffer: PBS, pH 7.7, containing 0.01% sodium azide

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -70°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.

Research Area: Signaling, Receptors

Restrictions: For Research Use only

Images

Immunohistochemical staining of Pancreas using anti- GPR119 antibody ABIN122117