LPAR5
Reactivity: Human
Host: Rabbit
Polyclonal
FITC
Application Notes
Immunohistochemistry with formalin fixed paraffin embedded tissues: 1.5 -4 μg/mL (for details please see Protocols below). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
PBS, 0.09 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-80 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
GPR92/GPR93 binds and is activated by compounds based on the lysophosphatidic acid (LPA) backbone. The binding of LPA to GPR92 was of high affinity and led to an increase in both phosphoinositide hydrolysis and c-AMP production. GPR92 is atypical in that it has a low sequence homology with the classic LPA receptors (21-22 % ). The expression of GPR92 is mainly found in brain, testis, heart, placenta, spleen, lung, and gut. Notably, GPR92 is highly expressed in the lymphocyte compartment of the gastrointestinal tract. It is the most abundant GPCR that is activated by LPA found in the small intestinal intraepithelial CD8+ cytotoxic T cells.Synonyms: 93, G-protein coupled receptor 92, LPA receptor 5, LPA-5, Lysophosphatidic acid receptor 5