Neurotensin Receptor 2 (NTSR2) antibody

Antigen: Neurotensin Receptor 2 (NTSR2)

Synonyms: NT2R, NTRL, NTR2, NTSR2

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN122343

Additional Information

Alternative name: Neurotensin receptor type 2

Swiss-Prot: O95665

Immunogen: Synthetic Peptide - KLH conjugated

Description: NTR2, a Neurotensin Receptor, is primarily expressed in brain neurons and astrocytes. It is activated by neurotensin and by levocabastine, a histamine H1 antagonist. NTR2 expression has been documented primarily in the brain, detailed localization data is available from rat and mouse brains. ESTs have been isolated from brain. Alternate Names: Levocabastine-Sensitive Neurotensin Receptor, NTR2 Receptor, NTSR2, NT-R-2.

Specificity: Reacts with Neurotensin Receptor Type 2 (.The immunizing peptide shows 77% identity (88% similarity) with Mouse and 72% identity (88 % similarity) with Rat

Application Details

Application Notes: Immunohistochemistry with formalin fixed paraffin embedded tissues: 4-7 ug/ml Antigen Retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Concentration: 1.0 mg/ml

Buffer: PBS, pH 7.7, containing 0.01% Sodium Azide as preservative.

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.

Restrictions: For Research Use only

Images

Immunohistochemical staining of Brain (Neurons) using anti- NTSR2 antibody ABIN122343