NPFFR2 antibody (C-Term)

Catalog No. ABIN122459

Product Details anti-NPFFR2 Antibody

Target: NPFFR2 (NPFF2) (Neuropeptide FF Receptor 2 (NPFF2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPFFR2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects Neuropeptide FF receptor 2 / NPFFR2 at C-term.

Purification: Immunoaffinity chromatography

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunohistochemistry with formalin-fixed paraffin embedded tissues: 4-7 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for NPFFR2

Target: NPFFR2 (NPFF2) (Neuropeptide FF Receptor 2 (NPFF2))

Alternative Name: Neuropeptide FF Receptor 2 (NPFF2 Products)

Synonyms: GPR74 antibody, HLWAR77 antibody, NPFF2 antibody, NPGPR antibody, Gpr74 antibody, HG31 antibody, Npff2 antibody, Npgpr antibody, neuropeptide FF receptor 2 antibody, NPFFR2 antibody, Npffr2 antibody

Background: The Neuropeptide FF 2 Receptor (NPFF2/HLWAR77/NPGPR) is a neuropeptide receptor GPCR. This receptor has high affinity for NPAF and NPFF, and is also weakly activated by FMRF-amide (Phe-Met-Arg-Phe-amide) and a variety of related peptides. The receptor is expressed in brain regions associated with opiate activity, consistent with the pain-modulating activity of these peptides, and in adipose tissue, suggesting other physiological and pathophysiological activities for FMRF-amide neuropeptides. Two isoforms are produced by alternative splicing.Synonyms: G-protein coupled receptor, G-protein coupled receptor 74, GPR74, NPFF2, NPFFR2, NPGPR, Neuropeptide G-protein coupled receptor

Gene ID: 10886

UniProt: Q9Y5X5

Pathways: cAMP Metabolic Process