CCKAR antibody (N-Term)

Catalog No. ABIN122572

Product Details anti-CCKAR Antibody

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCKAR antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Reacts with Cholecystokinin A Receptor (family: GPCR, subfamily: Cholecystokinin)

Purification: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunohistochemistry with formalin fixed paraffin embedded tissues: 3-6,8 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CCKAR

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Alternative Name: CCK-A Receptor (CCKAR Products)

Synonyms: CCK-XL antibody, cck-a antibody, cck1-r antibody, cckar-A antibody, cckbr antibody, cckra antibody, CCKAR antibody, CCK-A antibody, CCK1-R antibody, CCKRA antibody, AW106902 antibody, Cck-ar antibody, CCK-AR antibody, cholecystokinin A receptor antibody, cholecystokinin A receptor L homeolog antibody, CCKAR antibody, cckar.L antibody, Cckar antibody

Background: Cholecystokinin A receptor, a Cholecystokinin Receptor, binds sulfated CCK, particularly CCK8. The CCKA receptor mediates gallbladder contraction, gastric emptying, relaxation of the sphincter of Oddi, and insulin secretion. It is also involved in pancreatic growth, enzyme secretion, and tumorigenesis. Cholecystokinin A receptor has been reported in brain, colon, gall bladder, gastrointestinal tract, kidney, pancreas, small intestine, spinal cord, and stomach. ESTs have been isolated from mouse kidney and heart libraries.Synonyms: CCKA Receptor, CCKAR, CCKRA, Cholecystokinin receptor type A, Cholecystokinin-1 receptor

Gene ID: 886

UniProt: P32238

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Feeding Behaviour