PAK6 antibody (Linker Domain)
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- Target See all PAK6 Antibodies
- PAK6 (P21-Activated Kinase 6 (PAK6))
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Binding Specificity
- Linker Domain
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PAK6 antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- Reacts with P21-Activated Kinase 6 (PAK6) (family: Protein Kinase, subfamily: PAK (STE20))
- Characteristics
- Synonyms: p21-activated kinase 6, PAK-6, Serine/threonine-protein kinase PAK 6, PAK5, PAK-5
- Purification
- Peptide immunogen affinity column
- Immunogen
- Synthetic peptide - KLH conjugatedEpitope: Linker domain of humanGenename: PAK6
- Top Product
- Discover our top product PAK6 Primary Antibody
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- Application Notes
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Immunohistochemistry on paraffin embedded sections: 3,5 μg/mLAntigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.7, containing 0.01 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-80 °C
- Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- PAK6 (P21-Activated Kinase 6 (PAK6))
- Alternative Name
- PAK6 (PAK6 Products)
- Synonyms
- PAK5 antibody, 4732456M09 antibody, pak6 antibody, si:ch211-158b22.3 antibody, p21 (RAC1) activated kinase 6 antibody, p21 protein (Cdc42/Rac)-activated kinase 6 antibody, p21 protein (Cdc42/Rac)-activated kinase 6b antibody, PAK6 antibody, Pak6 antibody, pak6b antibody
- Background
- PAK6, a PAK (STE20) type protein kinase, contains a N-terminal Cdc42/Rac interactive binding (CRIB) motif and a C-terminal kinase domain. The protein has been shown to bind to GTP-Cdc42 and GTP-Rac, however, in contrast to most PAKs, kinase activity was not stimulated by Cdc42 or Rac, but could be stimulated by androgen receptor (AR) binding. PAK6 protein also has been shown to bind to estrogen receptor alpha. PAK6 also has been called P21-Activated Kinase 5 (PAK5), however, PAK5 is a distinct gene found on chromosome 20 p12.2. PAK6 expression has been documented in normal human brain, breast, prostate and testis. ESTs have been isolated from several tissue libraries, including normal brain and testis and cancerous cervix and smooth muscle.Synonyms: PAK-5, PAK-6, PAK5, Serine/threonine-protein kinase PAK 6, p21-activated kinase 6
- Gene ID
- 56924
- UniProt
- Q9NQU5
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