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Cholinergic Receptor, Muscarinic 1 (CHRM1) antibody

Antigen

Cholinergic Receptor, Muscarinic 1 (CHRM1)

Synonyms M1, HM1, M1R, MGC30125, Chrm-1, mAChR, CHRM1, DKFZp459P0517
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human, Mouse (Murine)

Application
Alternatives Western Blotting (WB)
Catalog no. ABIN122728
Quantity 0.2 mg  (1.0 mg/ml)  (Variants)
Price 420.00 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

Additional Information

Alternative name Muscarinic acetylcholine receptor M1
Swiss-Prot P11229
Immunogen Fusion protein containing amino acids 269-320 from human m1 AChR.
Description Acetylcholine receptors (AChRs) mediate synaptic transmission at the neuromuscular junction. The channel-linked AChR that mediates rapid, excitatory actions of acetylcholine is called nicotinic AChR (nAChR) because it can be activated by nicotine. The non-channel linked AChR that medicates the slow actions of acetylcholine, which can be either inhibitory or excitatory, is called muscarinic AChR (mAChR) because it can be activated by muscarine. The mAChRs are present in neurons of the central and peripheral nervous systems, cardiac and smooth muscle and various exocrine glands. There are 5 subtypes (m1-m5) of the receptor that have a tissue specific pattern of expression. The m1 receptor is localized primarily in brain tissue. Alternate Names: Muscarinic acetylcholine receptor M1, CHRM1.
Specificity ABIN122728 detects recombinant muscarinic acetylcholine receptor 1 (m1AChR). This sequence is completely conserved in mouse, rat, and bovine protein

Application Details

Application Notes Western Blot (2 ug/ml): detects an ~64 kDa protein representing recombinant mouse m1AChR. This antibody is not recommended for Immunohistochemistry procedures. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 1.0 mg/ml
Buffer PBS containing 1 mg/ml BSA as stabilizer and 0.05% Sodium Azide as preservative.
Storage Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Research Area Neurotransmitters, Hormones, Receptors
Restrictions For Research Use only

Alternatives

Alternatives for antigen "Cholinergic Receptor, Muscarinic 1 (CHRM1)", type "Antibodies"
Hosts Goat (3), Rabbit (3)
Reactivities Human (5), Rat (Rattus) (5), Mouse (Murine) (4), Dog (Canine) (2)
Applications Western Blotting (WB) (5), ELISA (2), Enzyme Immunoassay (EIA) (2), Immunofluorescence (IF) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)