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Antibodies
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anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Pol...
Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1/2 (GNAI1/GNAI2) antibody
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN122766 |
| Quantity |
0.1 mg (1.0 mg/ml) (Variants) |
| Price |
420.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: GNAI1, Guanine nucleotide-binding protein G(i) alpha-1 subunit
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Alternative name
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G protein alpha inhibitor 1 (+ alpha 2)
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Gene ID
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2770
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Swiss-Prot
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P63096
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Immunogen
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Synthetic peptide corresponding to residues K(346) N N L K D C G L F(355) of human GProtein alpha Inhibitor 1/2. Remarks: This sequence is completely conserved in human, rat, guinea pig, hamster,bovine, hydra, octopus, Xenopus, chicken, canine, spiny dogfish, great pond snail,starfish, and American lobster G protein alpha inhibitor 1/2. ABIN122766 immunizing peptide (ABIN126381) is available for use in Neutralization and Controlprocedures.
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Description
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The G protein family of signal transducers includes the alpha, beta, gamma subunits andthe effector which are most clearly distinguished by their different alpha chains. The familyalso includes Gs and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylatecyclase, Go, a protein of unknown function that is abundantly expressed in brain, andtransducin 1 and 2, proteins involved in retinal phototransduction. The G proteins possessGTPase activity and are components of a complex membrane signaling system thatincludes membrane-bound receptors. The system exists to modulate extracellular signalsas they are transmitted into the cell.
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Specificity
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This antibody detects G protein alpha inhibitor 1/2 from human, rat, and mouse tissuesand cells.
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Application Notes
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Western Blot: 1 ug/ml, this antibody detects an ~38 kDa protein representing G proteinalpha inhibitor 1/2 from HeLa cell lysate. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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1.0 mg/ml
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Buffer
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PBS containing 1 mg/ml BSA as stabilizer and 0.05% sodium azide aspreservative.
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Storage
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Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Restrictions
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For Research Use only
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Alternatives for antigen "Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1/2 (GNAI1/GNAI2)", type "Antibodies"
Alternatives 
