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AKT2 antibody (V-Akt Murine Thymoma Viral Oncogene Homolog 2)

Details for Product anti-AKT2 Antibody No. ABIN123279, Supplier: Login to see New
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(405), (126), (100), (30), (28), (25), (24), (21), (21), (19), (19), (19), (19), (1), (1), (1)
(311), (77), (12), (10), (4), (2)
This AKT2 antibody is un-conjugated
(19), (19), (18), (16), (15), (15), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(351), (225), (146), (83), (49), (29), (28), (22), (19), (12), (11), (5), (4), (3), (1), (1), (1)
Pubmed 5 references available
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Quantity 0.1 mg
Shipping to United States ( )
Immunogen Human Akt2. AA Sequence:319-331
Purification Protein G chromatography
Alternative Name AKT2 / PKB beta (AKT2 Antibody Abstract)
Background Akt, protein kinase B (PKB), is a serine/threonine kinase, which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphatidylinositol 3-kinase (PI 3-kinase). Akt2 is amplified and overexpressed in some human cancers.
UniProt P31751
Research Area Signaling
Pathways PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, TLR Signaling
Application Notes Western blotting (1-2 ug/ml). Use HeLa as positive control. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.02 % sodium azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C for one month or at -20 °C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-AKT2 antibody (V-Akt Murine Thymoma Viral Oncogene Homolog 2) (ABIN123279) Western blot analysis of Akt2/3 using ABIN123279 at 1 µg/ml against 15 µg of HeLa lys...
General Kandel, Hay: "The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB." in: Experimental cell research, Vol. 253, Issue 1, pp. 210-29, 1999 (PubMed).

Cantley, Neel: "New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 8, pp. 4240-5, 1999 (PubMed).

Alessi, Andjelkovic, Caudwell et al.: "Mechanism of activation of protein kinase B by insulin and IGF-1." in: The EMBO journal, Vol. 15, Issue 23, pp. 6541-51, 1997 (PubMed).

Cheng, Ruggeri, Klein et al.: "Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 8, pp. 3636-41, 1996 (PubMed).

Cheng, Godwin, Bellacosa et al.: "AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 19, pp. 9267-71, 1992 (PubMed).

Catalog No. ABIN123279

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