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Details for Product No. ABIN123281

Runt-Related Transcription Factor 1 (RUNX1) (AA 231-245) antibody

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Antigen
Synonyms AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, AML1-EVI-1, AI462102, Cbfa2, Pebp2a2, Pebpa2b, Aml1, runxa, Runx-1, XAML, Xaml1, aml, aml-1, aml1, aml1-evi-1, amlcr1, cbfa2, evi-1, pebp2ab, RUNX1, runx1
Epitope
»Alternatives AA 231-245
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN123281
Quantity 0.1 mg
Price
489.50 $   Plus shipping costs $45.00
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Availability Discontinued
Immunogen Synthetic peptide corresponding to a sequence that is homologous in AML-1 and AML-1/ETO (amino acids 231 to 245 of human origin) AA Sequence:AFNPQPQSQMQDTRQ
Purification Protein G chromatography
Alternative Name RUNX1
Background AML-1 is a DNA-binding protein which specifically interacts with a sequence belonging to the group of enhancer core motifs, TGT/cGGT. The AML1 gene on chromosome 21 is disrupted in the (8,21)(q22,q22) translocation associated with acute myelogenous leukemia and encodes a protein with a central 118-amino-acid domain with 69% homology to the Drosophila pair-rule gene, runt. AML-1 translocation is frequently observed in acute myeloid leukemia. It is a key transactivator of tissue-specific genes of the hematopoietic and bone lineages. Alternate Names: CBFA2 / Runx1.
UniProt Q01196
Application Notes Western blot: 2-5 ug/ml. Recommended Positive Control: Ramos, Raw. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.2 % gelatin, 0.05 % sodium azide
Preservative Sodium azide
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C. Avoid repeated freezing and thawing. Centrifuge vial before opening. Shelf Life: One year from despatch.
Expiry Date 12 months
Davis, McGhee, Meyers: "The ETO (MTG8) gene family." in: Gene, Vol. 303, pp. 1-10, 2003 (PubMed).

Alternatives for antigen "Runt-Related Transcription Factor 1 (RUNX1)", type "Antibodies"
Hosts (151), (41), (3), (3)
Reactivities (190), (96), (86), (42), (42), (24), (12), (5), (3), (3), (1), (1), (1)
Applications (148), (109), (44), (40), (33), (31), (11), (7), (3), (3), (2), (2), (1)
Conjugates (6), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4)
Epitopes (18), (17), (13), (12), (10), (9), (6), (5), (5), (4), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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