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Runt-Related Transcription Factor 1 (RUNX1) (AA 231-245) antibody

Details for Product No. ABIN123281
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Antigen
Epitope
AA 231-245
(21), (16), (13), (13), (12), (12), (10), (8), (7), (5), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(207), (99), (91), (42), (42), (24), (12), (5), (4), (3), (2), (2)
Host
Rabbit
(172), (41), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(7), (6), (5), (4), (4), (4), (4), (4), (4), (4), (4), (1), (1), (1)
Application
Western Blotting (WB)
(163), (114), (44), (40), (36), (34), (20), (11), (2), (2), (1)
Pubmed 1 reference available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Discontinued
Catalog No. ABIN123281
500.50 $
Plus shipping costs $45.00
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Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide corresponding to a sequence that is homologous in AML-1 and AML-1/ETO (amino acids 231 to 245 of human origin) AA Sequence:AFNPQPQSQMQDTRQ
Purification Protein G chromatography
Alternative Name RUNX1
Background AML-1 is a DNA-binding protein which specifically interacts with a sequence belonging to the group of enhancer core motifs, TGT/cGGT. The AML1 gene on chromosome 21 is disrupted in the (8,21)(q22,q22) translocation associated with acute myelogenous leukemia and encodes a protein with a central 118-amino-acid domain with 69% homology to the Drosophila pair-rule gene, runt. AML-1 translocation is frequently observed in acute myeloid leukemia. It is a key transactivator of tissue-specific genes of the hematopoietic and bone lineages. Alternate Names: CBFA2 / Runx1.
UniProt Q01196
Application Notes Western blot: 2-5 ug/ml. Recommended Positive Control: Ramos, Raw. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.2 % gelatin, 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C. Avoid repeated freezing and thawing. Centrifuge vial before opening. Shelf Life: One year from despatch.
Expiry Date 12 months
Supplier Images
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 231-245) antibody Western Blot analysis of AML-1 in Daudi cell lysate.
General Davis, McGhee, Meyers: "The ETO (MTG8) gene family." in: Gene, Vol. 303, pp. 1-10, 2003 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN123281
500.50 $
Plus shipping costs $45.00
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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