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Protective Antigen (PA) (AA 238-254) antibody

Details for Product No. ABIN123283
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Antigen
Epitope
AA 238-254
(2), (1), (1), (1)
Reactivity
Bacillus anthracis
(21)
Host
Rabbit
(16), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1)
Application
Western Blotting (WB)
(20), (15), (5), (1), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN123283
Quantity 0.2 mL
Price
456.50 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Discontinued
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Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptides corresponding to amino acids 238-254 of the Anthrax PA protein (~83 kD)
Purification Serum
Background Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxic entry into cells. PA is secreted from Bacillus anthracis as an 83 kDa (PA83) protein which is cleaved by furin protease, releasing a 20 kDa fragment. The 63 kDa portion (PA63) of the cleavage product forms a heptamer, which binds the toxins LF and EF. This complex enters via receptor-mediated endocytosis where LF and EF exert their toxic effects.
UniProt P13423
Application Notes Western blot: 1:1000. Recommended Positive Control: PA recombinant protein. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.2 % gelatin and 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
Supplier Images
anti-Protective Antigen (PA) (AA 238-254) antibody Western blot analysis of Anthrax PA in recombinant protein using ABIN123283 (lane B) at 1:1000 dilution. Lane A showsthepre-bleed
General Collier, Young: "Anthrax toxin." in: Annual review of cell and developmental biology, Vol. 19, pp. 45-70, 2003 (PubMed).

Hosts (16), (5)
Reactivities (21)
Applications (20), (15), (5), (1), (1), (1)
Conjugates (1)
Epitopes (2), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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