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Ankyrin Repeat and SOCS Box-Containing 11 (ASB11) (AA 40-51), (AA 250-265) antibody

Details for Product No. ABIN123291
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Antigen
Epitope
AA 40-51, AA 250-265
(4), (3), (2), (2), (2), (1)
Reactivity
Human
(13), (3), (1)
Host
Rabbit
(12), (3)
Clonality
Polyclonal
Application
Western Blotting (WB)
(15), (5)
Pubmed 2 references available
Quantity 0.2 mL
Shipping to United States (Change)
Availability Discontinued
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Catalog No. ABIN123291
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Immunogen Synthetic peptides corresponding to amino acids 40-51 and 250-265 of human Asb-11
Purification Protein G chromatography
Alternative Name ASB11
Background The ankyrin repeat and SOCS box-containing (Asb) protein family is comprised of members which each contain 'SOCS boxes' but differ from other families of protein in the motifs they contain upstream of the SOCS box (1). SOCS boxes are carboxy-terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases.
UniProt Q8WXH4
Research Area Chromatin and Nuclear Signaling, Cell Cycle, Transcription Factors
Application Notes Western blotting (1:500-1:1000). Recommended Positive Control: human liver. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.02 % sodium azide and 0.1 mg/ml BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
Supplier Images
anti-Ankyrin Repeat and SOCS Box-Containing 11 (ASB11) (AA 40-51), (AA 250-265) antibody Western blot analysis of Asb-11 in 15 ugs of human liver cell lysate using ABIN123291 at 1:1000dilution.
General Krebs, Hilton: "SOCS proteins: negative regulators of cytokine signaling." in: Stem cells (Dayton, Ohio), Vol. 19, Issue 5, pp. 378-87, 2001 (PubMed).

Wang, Campbell: "Cytokine signaling in the brain: putting a SOCS in it?" in: Journal of neuroscience research, Vol. 67, Issue 4, pp. 423-7, 2002 (PubMed).

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