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Activating Transcription Factor 2 (ATF2) antibody
| Antigen | Activating Transcription Factor 2 (ATF2) |
| Synonyms | HB16, CREB2, TREB7, CRE-BP1, MGC111558, ATF2, MGC142504, CHN1, CG12850, CG3749, dATF-2, DmelCG30420, CG30420 |
| Clonality | Polyclonal |
| Host |
Alternatives Rabbit |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Western Blotting (WB)
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2 references available |
| Catalog no. | ABIN123294 |
| Quantity | 0.1 mg (0.5 mg/ml) (Variants) |
| Price | 265.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Alternative name | ATF2 |
| Swiss-Prot | P15336 |
| Immunogen | Swiss-Prot ID: P15336 |
| Description | ATF-2 is a member of the group of bZip transcription factors. Heterodimer formation between members of the bZip group is common and is believed to add diversity to the cis-acting elements at which binding of the dimers is directed. Specifically, ATF-2 may dimerize with c-Jun, as occurs in response to E1a, and in so doing shift the binding preference of c-Jun toward ATF/CRE sites (1-3). Deletion analysis has indicated that the N-terminal region of ATF-2 containing threonine at residues 69 and 71 are essential for this purpose. These threonine residues are phosphorylated by JNK/SAPK for transcriptional activation. |
| Specificity | This antibody was generated by immunizing rabbits with a synthetic peptide containing amino acids 13-27. |
Application Details
| Application Notes | Western blot: 2 ug/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
| Concentration | 0.5 mg/ml |
| Buffer | PBS containing 0.02% sodium azide. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch. |
| Research Area | Immunology, Innate Immunity, Transcription Factors |
| Restrictions | For Research Use only |
Images
| Staining of 293 cell lysate. using ABIN123294 Detection of ATF2 in 293 cell lysate using ABIN123294 at 2 µg/ml. |
Publications
| Publications |
Hai, Curran: "Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 9, pp. 3720-4, 1991 (PubMed).
Benbrook, Jones: "Heterodimer formation between CREB and JUN proteins." in: Oncogene, Vol. 5, Issue 3, pp. 295-302, 1990 (PubMed). |
Alternatives
Alternatives for antigen "Activating Transcription Factor 2 (ATF2)", type "Antibodies"




Alternatives