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Activating Transcription Factor 2 (ATF2) antibody

Antigen

Activating Transcription Factor 2 (ATF2)
Synonyms HB16, CREB2, TREB7, CRE-BP1, MGC111558, ATF2, MGC142504, CHN1, CG12850, CG3749, dATF-2, DmelCG30420, CG30420
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB)
2 references available
Catalog no. ABIN123294
Quantity 0.1 mg  (0.5 mg/ml)  (Variants)
Price 341.00 $   Plus shipping costs $45.00
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anti-Activating Transcription Factor 2 (ATF2) antibody

anti-Activating Transcription Factor 2 (ATF2) antibody (2)

Additional Information
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Alternative name ATF2
UniProt P15336
Immunogen Swiss-Prot ID: P15336
Cross-Reactivity Human
Description ATF-2 is a member of the group of bZip transcription factors. Heterodimer formation between members of the bZip group is common and is believed to add diversity to the cis-acting elements at which binding of the dimers is directed. Specifically, ATF-2 may dimerize with c-Jun, as occurs in response to E1a, and in so doing shift the binding preference of c-Jun toward ATF/CRE sites (1-3). Deletion analysis has indicated that the N-terminal region of ATF-2 containing threonine at residues 69 and 71 are essential for this purpose. These threonine residues are phosphorylated by JNK/SAPK for transcriptional activation.

Application Details
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Application Notes Western blot: 2 ug/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 0.5 mg/ml
Purification Purified
Buffer PBS containing 0.02% sodium azide.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Research Area Immunology, Innate Immunity, Transcription Factors
Restrictions For Research Use only

Publications
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Hai, Curran: "Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 9, pp. 3720-4, 1991 (PubMed).

Benbrook, Jones: "Heterodimer formation between CREB and JUN proteins." in: Oncogene, Vol. 5, Issue 3, pp. 295-302, 1990 (PubMed).

Alternatives
Application Details Publications Images Variants back to top

Alternatives for antigen "Activating Transcription Factor 2 (ATF2)", type "Antibodies"
Hosts Rabbit (359), Mouse (13), Goat (7), Sheep (7)
Reactivities Human (380), Mouse (Murine) (267), Rat (Rattus) (266), Cow (Bovine) (130), Horse (Equine) (109), Dog (Canine) (95), Chicken (74), Pig (Porcine) (72), Guinea Pig (18), Rabbit (18), Bird (Avian) (2), Cat (Feline) (1), Xenopus laevis (1)
Applications Western Blotting (WB) (185), Immunofluorescence (IF) (166), Immunohistochemistry (IHC) (110), ELISA (109), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (78), Immunoprecipitation (IP) (64), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (27), Immunocytochemistry (ICC) (12), Immunoelectron Microscopy (IEM) (9), Dot Blot (Dot) (6), Electrophoretic Mobility-Shift Assay (EMSA) (3), Immunohistochemistry (Frozen Sections) (IHC (fro)) (3), Flow Cytometry (FACS) (1), Functional Studies (Func) (1)
Conjugates Alexa Fluor 350 (9), Alexa Fluor 488 (9), Alexa Fluor 555 (9), Alexa Fluor 647 (9), Biotin (9), Cy3 (9), Cy5 (9), Cy5.5 (9), Cy7 (9), FITC (9), Gold (9), HRP (9), PE (9), PE,Cy3 (8), PE,Cy5 (8), PE,Cy5.5 (8), PE,Cy7 (8), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
Epitopes C-Term (25), pSer472 (22), pSer322 (21), pSer44 (21), pSer94 (21), pThr51 (21), pThr53 (18), pThr69,pThr71 (18), pSer490,pSer498 (14), N-Term (7), pSer498,pSer490 (5), pThr71 (5), pSer62,pSer44 (4), pThr69, pThr51 (4), pThr69,pThr51 (4), pThr71,pThr53 (4), pSer112, pSer94 (3), pSer112,pSer94 (3), pSer44, pSer62 (3), pSer490, pSer498 (3), pSer62, pSer44 (3), pThr51, pThr69 (3), pThr53, pThr71 (3), pThr55, pThr73 (3), pThr71, pThr53 (3), pThr73, pThr55 (3), pThr73,pThr55 (3), Ab-112 or 94 (2), Ab-62 or 44 (2), Ab-69 or 51 (2), Ab-71 or 53 (2), Ab-73 or 55 (2), Internal Region (2), Ser44 (2), Ser94 (2), pSer112 or 94 (2), pSer62 or 44 (2), pSer94, pSer112 (2), pThr69 or 51 (2), pThr71 or 53 (2), pThr73 or 55 (2), AA 13-27 (1), AA 95-211 (1), Center (1), Internal Region,AA 317-347 (1), Phosphospecific (1), Ser112, Ser94 (1), Ser62 (1), Ser62, Ser44 (1), Ser69, Ser71 (1), Ser94, Ser112 (1), Thr51 (1), Thr71, Thr51 (1), Thr73, Thr55 (1), Thr99, Thr51 (1), pSer112 (1), pSer44,pSer62 (1), pSer480 (1), pSer62 (1), pSer90 (1), pSer94, pSer119 (1), pSer94,pSer112 (1), pThr51,pThr69 (1), pThr53,pThr71 (1), pThr55,pThr73 (1), pThr69 (1), pThr69, pThr71 (1), pThr69,pThr51,pThr71,pThr53 (1), pThr73 (1)