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Details for Product No. ABIN123330

Deoxyribonuclease II, Lysosomal (DNASE2) (AA 347-360) antibody

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Antigen
Synonyms
Dnase2a, DNL, DNL2, DNASE2A, Dnase2, CG7780, DNase, DNase 1, DNase-1, DNase1, Dmel\\CG7780, dDNase II, DNASE2, deoxyribonuclease-2-beta, DLAD, DNASE2B, dnase2b, dnase2, MGC80103, LOC733868, fa92d01, w ... show more
Epitope
»Alternatives AA 347-360
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN123330
Quantity 0.1 mg
Price
654.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Peptide corresponding to amino acids 347 to 360 of human DNase precursor
Purification Protein G chromatography
Alternative Name Deoxyribonuclease-2-alpha
Background DNase II causes chromatin condensation and DNA fragmentation. The DNase II gene encodes for a proenzyme of approximate molecular mass of 40 kDa. The active enzyme consists of a heterodimer of 32 kDa and 12 kDa.
UniProt O00115
Application Notes Western blot: 2 - 4 ug/ml. Recommended Positive Control: human spleen. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
Liu, Zou, Slaughter et al.: "DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis." in: Cell, Vol. 89, Issue 2, pp. 175-84, 1997 (PubMed).

Wyllie: "Apoptosis. An endonuclease at last." in: Nature, Vol. 391, Issue 6662, pp. 20-1, 1998 (PubMed).

Enari, Sakahira, Yokoyama et al.: "A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD." in: Nature, Vol. 391, Issue 6662, pp. 43-50, 1998 (PubMed).

Alternatives for antigen "Deoxyribonuclease II, Lysosomal (DNASE2)", type "Antibodies"
Hosts (31), (2)
Reactivities (33), (13), (13), (11), (11), (11)
Applications (24), (10), (9), (6), (5), (3), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (3), (1), (1)
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