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Details for Product No. ABIN123347

FOS-Like Antigen 2 (FOSL2) (AA 377-391) antibody

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Antigen
Synonyms Fra-2, Fra2, FRA2, fra2, wu:fl17h04, xx:fl17h04, zgc:158347, PLB1, fra-2, FOSL2
Epitope
»Alternatives AA 377-391
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN123347
Quantity 0.1 mg
Price
654.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Peptide corresponding to amino acids 377 to 391 of human GFRa-2
Purification Protein G Chromatography
Alternative Name Fos-related antigen 2
Background GFRa-2, also known as NTNRa, GDNFRb, Ret ligand 2 (RETL2) or TGFb-related neurotrophic factor receptor 2 (TNR2) binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. GDNF (glial cell line-derived neurotrophic factor) is a potent survival factor for central and peripheral neurons. Physiological responses to GDNF require the presence of a novel glycosylphophadidylinositol linked protein GDNFRa. Alternate Names: GDNFbeta / RETL2.
UniProt P15408
Research Area Growth Factors, Receptors
Application Notes Western blot at 1-2 ug/ml dilution. HeLa cell lysate can be used at positive control and a 52 kDa band should be detected. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.02% sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 4-8°C for one month or at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
Kotzbauer, Lampe, Heuckeroth et al.: "Neurturin, a relative of glial-cell-line-derived neurotrophic factor." in: Nature, Vol. 384, Issue 6608, pp. 467-70, 1997 (PubMed).

Baloh, Tansey, Golden et al.: "TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret." in: Neuron, Vol. 18, Issue 5, pp. 793-802, 1997 (PubMed).

Klein, Sherman, Ho et al.: "A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor." in: Nature, Vol. 387, Issue 6634, pp. 717-21, 1997 (PubMed).

Alternatives for antigen "FOS-Like Antigen 2 (FOSL2)", type "Antibodies"
Hosts (51), (6)
Reactivities (57), (24), (24), (17), (13), (13), (12), (12), (4), (1), (1)
Applications (41), (20), (16), (16), (10), (4), (3), (3), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (5), (4), (3), (3), (2), (2), (1), (1), (1), (1)
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