FOS-Like Antigen 2 (FOSL2) (AA 377-391) antibody

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Antigen
Epitope
AA 377-391
(22), (18), (16), (13), (11), (10), (9), (6), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(132), (33), (32), (6), (4), (4), (3), (1), (1)
Host
Rabbit
(116), (16)
Clonality
Polyclonal
Conjugate
Un-conjugated
(8), (8), (8), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(101), (62), (35), (17), (11), (11), (4), (3), (3), (3), (2), (1), (1), (1)
Pubmed 3 references available
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Quantity 0.1 mg
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Immunogen Peptide corresponding to amino acids 377 to 391 of human GFRa-2
Purification Protein G Chromatography
Alternative Name Fos-related antigen 2 (FOSL2 Antibody Abstract)
Background GFRa-2, also known as NTNRa, GDNFRb, Ret ligand 2 (RETL2) or TGFb-related neurotrophic factor receptor 2 (TNR2) binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. GDNF (glial cell line-derived neurotrophic factor) is a potent survival factor for central and peripheral neurons. Physiological responses to GDNF require the presence of a novel glycosylphophadidylinositol linked protein GDNFRa. Alternate Names: GDNFbeta / RETL2.
UniProt P15408
Research Area Growth Factors, Receptors
Application Notes Western blot at 1-2 ug/ml dilution. HeLa cell lysate can be used at positive control and a 52 kDa band should be detected. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.02% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 4-8°C for one month or at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-FOS-Like Antigen 2 (FOSL2) (AA 377-391) antibody (ABIN123347) Western blot analysis of GFRa-2 in HeLa whole cell lysate using ABIN123347 at 1 µg/ml.
General Klein, Sherman, Ho et al.: "A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor." in: Nature, Vol. 387, Issue 6634, pp. 717-21, 1997 (PubMed).

Baloh, Tansey, Golden et al.: "TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret." in: Neuron, Vol. 18, Issue 5, pp. 793-802, 1997 (PubMed).

Kotzbauer, Lampe, Heuckeroth et al.: "Neurturin, a relative of glial-cell-line-derived neurotrophic factor." in: Nature, Vol. 384, Issue 6608, pp. 467-70, 1997 (PubMed).

Catalog No. ABIN123347

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