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FOS-Like Antigen 2 (FOSL2) antibody
| Antigen | FOS-Like Antigen 2 (FOSL2) |
| Synonyms | FOSL2 |
| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Human, Mouse (Murine), Rat (Rattus) |
| Conjugate |
Alternatives Un-conjugated |
| Application |
Alternatives Western Blotting (WB) |
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3 references available |
| Catalog no. | ABIN123347 |
| Quantity | 0.1 mg (0.5 mg/ml) (Variants) |
| Price | 594.00 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Will be delivered in 6 to 8 Business Days |
Additional Information
| Alternative name | Fos-related antigen 2 |
| UniProt | P15408 |
| Immunogen | Peptide corresponding to amino acids 377 to 391 of human GFRa-2 |
| Cross-Reactivity | Human, Mouse (Murine), Rat (Rattus) |
| Description | GFRa-2, also known as NTNRa, GDNFRb, Ret ligand 2 (RETL2) or TGFb-related neurotrophic factor receptor 2 (TNR2) binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. GDNF (glial cell line-derived neurotrophic factor) is a potent survival factor for central and peripheral neurons. Physiological responses to GDNF require the presence of a novel glycosylphophadidylinositol linked protein GDNFRa. Alternate Names: GDNFbeta / RETL2. |
Application Details
| Application Notes | Western blot at 1-2 ug/ml dilution. HeLa cell lysate can be used at positive control and a 52 kDa band should be detected. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
| Concentration | 0.5 mg/ml |
| Purification | Purified |
| Buffer | PBS containing 0.02% sodium azide |
| Storage | Store the antibody at 4-8°C for one month or at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch. |
| Research Area | Growth Factors, Receptors |
| Restrictions | For Research Use only |
Publications
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Kotzbauer, Lampe, Heuckeroth et al.: "Neurturin, a relative of glial-cell-line-derived neurotrophic factor." in: Nature, Vol. 384, Issue 6608, pp. 467-70, 1997 (PubMed).
Baloh, Tansey, Golden et al.: "TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret." in: Neuron, Vol. 18, Issue 5, pp. 793-802, 1997 (PubMed). Klein, Sherman, Ho et al.: "A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor." in: Nature, Vol. 387, Issue 6634, pp. 717-21, 1997 (PubMed). |
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Alternatives
Alternatives for antigen "FOS-Like Antigen 2 (FOSL2)", type "Antibodies"
| Hosts | Rabbit (37), Mouse (4) |
| Reactivities | Human (38), Rat (Rattus) (24), Mouse (Murine) (23), Chicken (3), Bird (Avian) (2), Hamster (2) |
| Applications | Western Blotting (WB) (24), Immunofluorescence (IF) (16), ELISA (13), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (10), Immunohistochemistry (IHC) (6), Electrophoretic Mobility-Shift Assay (EMSA) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Dot Blot (Dot) (1), Gel Shift (GS) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunoprecipitation (IP) (1) |
| Conjugates | Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1) |
| Epitopes | Internal Region (2), C-Term (1), Center (1), N-Term (1) |
Sponsorship
2013 BioMed Central Research Awards
2013 BioMed Central Research Awards
