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Details for Product No. ABIN123368

SET / I2PP2A (AA 66-81), (AA 135-151) antibody

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Antigen
Epitope
»Alternatives AA 66-81, AA 135-151
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN123368
Quantity 0.1 mg
Price
445.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Synthetic peptides of amino acids 66-81 and 135-151 of human INHAT-1Remarks: Sequence homology is 100% in mouse and rat.
Characteristics Synonyms: I-2PP2A, TAF-I, PHAPII, IGAAD, Phosphatase 2A inhibitor I2PP2A, Template-activating factorI, Inhibitor of granzyme A-activated DNase
Purification Protein G Chromatography
Background INHAT (inhibitor of acetyltransferases) complex binds to histones and masks them frombeing substrate for acetyltransferase. Endogenous INHAT subunits, which include theSet/TAF-Ibeta oncoprotein, associate with chromatin in vivo and can block coactivatormediated transcription when transfected in cells.
Gene ID 6418
UniProt Q01105
Application Notes Western blot: 1.0 - 2.0 ug/ml. Recommended positive control: Jurkat. An ~37 kDa band is observed. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.02% sodium azide and 0.1 mg/ml BSA
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date 12 months
Seo, Macfarlan, McNamara et al.: "Regulation of histone acetylation and transcription by nuclear protein pp32, a subunit of the INHAT complex." in: The Journal of biological chemistry, Vol. 277, Issue 16, pp. 14005-10, 2002 (PubMed).

Alternatives for antigen "SET / I2PP2A", type "Antibodies"
Hosts (5), (2)
Reactivities (7), (2), (1)
Applications (7), (4), (1), (1), (1)
Epitopes (2), (1), (1)
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