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Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A) (AA 87-103), (AA 231-246) antibody

Details for Product No. ABIN123369
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Antigen
Epitope
AA 87-103, AA 231-246
(13), (7), (7), (7), (6), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Chimpanzee, Human, Rhesus Monkey
(86), (29), (26), (14), (14), (12), (2), (2), (2)
Host
Rabbit
(64), (25)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(77), (43), (30), (27), (16), (12), (10), (5), (3)
Pubmed 1 reference available
Quantity 0.2 mL
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Availability Discontinued
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Catalog No. ABIN123369
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Immunogen Synthetic peptides of amino acids 87-103 and 231-246 of human INHAT-2AA Sequence: CPNLTHLNLSGNKIKDL / EERGQKRKREPEDEGE
Characteristics Synonyms: C15orf1, LANP, MAPM, PHAP1, Mapmodulin, Acidic leucine-rich nuclear phosphoprotein 32family member A, Potent heat-stable protein phosphatase 2A inhibitor I1PP2A, Acidicnuclear phosphoprotein pp32, Leucine-rich acidic nuclear protein, PutativeHLA-DR-associated protein I
Purification Protein G Chromatography
Alternative Name ANP32A
Background INHAT (inhibitor of acetyltransferases) complex binds to histones and masks them frombeing substrate for acetyltransferase. Endogenous INHAT subunits, which include theSet/TAF-Ibeta oncoprotein, associate with chromatin in vivo and can block coactivatormediated transcription when transfected in cells.
Gene ID 8125
UniProt P39687
Application Notes Western blot: 1/500 - 1/1000. Recommended positive control: HeLa. In HeLa, a 31 kDa band is observed. Otherapplications not tested. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.02% sodium azide and 0.1 mg/ml BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
anti-Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A) (AA 87-103), (AA 231-246) antibody Western blot detection of INHAT-2 using ABIN123369 at a 1:1000 dilution against 10 ug of HeLa cell lysate.
General Seo, Macfarlan, McNamara et al.: "Regulation of histone acetylation and transcription by nuclear protein pp32, a subunit of the INHAT complex." in: The Journal of biological chemistry, Vol. 277, Issue 16, pp. 14005-10, 2002 (PubMed).

Validation Images
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