Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (AA 425-439) antibody

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Antigen
Epitope
AA 425-439
(44), (44), (23), (13), (13), (8), (7), (7), (5), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(251), (137), (133), (1)
Host
Rabbit
(246), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(8), (8), (8), (4), (4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (2)
Application
Western Blotting (WB)
(198), (105), (59), (44), (43), (17), (8), (4), (3), (2), (1), (1)
Pubmed 1 reference available
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Quantity 0.1 mg
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Immunogen Synthetic peptide containing amino acids 425-439 of human p62dok
Purification Protein G Chromatography
Alternative Name DOK1 / p62 dok (DOK1 Antibody Abstract)
Background P62dok is a major substrate for many tyrosine kinases including c-kit, v-abl, vFPS, EGF, and PDGF. Upon phosphorylation by kinases, p62dok forms a complex with ras GTPase-activating protein.
UniProt Q99704
Application Notes Western blot: 1.0 - 2.0 ug/ml. Recommended Positive Control: Jurkat, Daudi, mouse NIH 3T3. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.02% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (AA 425-439) antibody (ABIN123407) Western blot analysis of p62dok using ABIN123407 at 2 ug/ml against 10 ug of Jurkat (...
General Yamanashi, Baltimore: "Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok." in: Cell, Vol. 88, Issue 2, pp. 205-11, 1997 (PubMed).

Catalog No. ABIN123407
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