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Details for Product No. ABIN123433

SUMO1/sentrin Specific Peptidase 1 (SENP1) (AA 578-590) antibody

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Antigen
Synonyms SuPr-2, 2310046A20Rik, D15Ertd528e, E330036L07Rik, suPr-2, senp1, senp1a, xsenp1, SENP1, Senp1, senp1b
Epitope
»Alternatives AA 578-590
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN123433
Quantity 0.1 mg
Price
445.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Synthetic peptide corresponding to aa 578-590 of human SENP1
Purification Protein G Chromatography.
Alternative Name SENP1
Background Covalent attachment of one protein to another is one of the more prominent posttranslational modifications in respect to size and ubiquity. Ubiquitin is the most familiar of the protein modifiers and its activation and transfer to target proteins has been studied extensively. Recently, a new group of ubiquitin-like proteins has been receiving a lot of attention. SUMO, or Sentrin, is one of the most intriguing. SUMO has been implicated in the stabilization of target proteins and/or their localization to sub-cellular complexes.
UniProt Q9P0U3
Research Area Proteolysis / Ubiquitin
Application Notes Western blot (1/500-1/1,000, observed size: 66 kD, positive control: Jurkat or NIH3T3 whole cell lysate). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.2% Gelatin as stabilizer and 0.05% Sodium Azide as preservative.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C for up to one month or at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
Müller, Hoege, Pyrowolakis et al.: "SUMO, ubiquitin's mysterious cousin." in: Nature reviews. Molecular cell biology, Vol. 2, Issue 3, pp. 202-10, 2001 (PubMed).

Kahyo, Nishida, Yasuda: "Involvement of PIAS1 in the sumoylation of tumor suppressor p53." in: Molecular cell, Vol. 8, Issue 3, pp. 713-8, 2001 (PubMed).

Alternatives for antigen "SUMO1/sentrin Specific Peptidase 1 (SENP1)", type "Antibodies"
Hosts (44), (2)
Reactivities (43), (23), (13), (12), (12), (12), (1)
Applications (36), (19), (12), (10), (8), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
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