SUMO1/sentrin Specific Peptidase 1 (SENP1) (AA 578-590) antibody

Details for Product No. ABIN123433
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Antigen
Epitope
AA 578-590
(16), (10), (7), (7), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(64), (35), (14), (12), (12), (12), (1)
Host
Rabbit
(71), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(62), (36), (20), (12), (10), (3), (1), (1), (1)
Pubmed 2 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Discontinued
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Catalog No. ABIN123433
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Immunogen Synthetic peptide corresponding to aa 578-590 of human SENP1
Purification Protein G Chromatography.
Alternative Name SENP1
Background Covalent attachment of one protein to another is one of the more prominent posttranslational modifications in respect to size and ubiquity. Ubiquitin is the most familiar of the protein modifiers and its activation and transfer to target proteins has been studied extensively. Recently, a new group of ubiquitin-like proteins has been receiving a lot of attention. SUMO, or Sentrin, is one of the most intriguing. SUMO has been implicated in the stabilization of target proteins and/or their localization to sub-cellular complexes.
UniProt Q9P0U3
Research Area Proteolysis / Ubiquitin
Application Notes Western blot (1/500-1/1,000, observed size: 66 kD, positive control: Jurkat or NIH3T3 whole cell lysate). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.2% Gelatin as stabilizer and 0.05% Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C for up to one month or at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
Supplier Images
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (AA 578-590) antibody Western blot analysis of SENP1 in 15 ugs of (A) Jurkat and (B) NIH3T3 cell lysate usingABIN123433 at 1:1000.
General Müller, Hoege, Pyrowolakis et al.: "SUMO, ubiquitin's mysterious cousin." in: Nature reviews. Molecular cell biology, Vol. 2, Issue 3, pp. 202-10, 2001 (PubMed).

Kahyo, Nishida, Yasuda: "Involvement of PIAS1 in the sumoylation of tumor suppressor p53." in: Molecular cell, Vol. 8, Issue 3, pp. 713-8, 2001 (PubMed).

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