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SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2) antibody

Antigen

SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2)

Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Application
Alternatives Western Blotting (WB)
1 reference available
Catalog no. ABIN123434
Quantity 0.2 ml  (0.5 mg/ml)  (Variants)
Price 319.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days

Additional Information

Alternative name SENP2
Gene ID 59343
UniProt Q9HC62
Immunogen Synthetic peptide of human SENP2
Cross-Reactivity Human, Mouse (Murine)
Description Covalent attachment of one protein to another is one of the more prominentposttranslational modifications in respect to size and ubiquity. Ubiquitin is the mostfamiliar of the protein modifiers and its activation and transfer to target proteins has beenstudied extensively. Recently, a new group of ubiquitin-like proteins has been receiving alot of attention. SUMO, or Sentrin, is one of the most intriguing. SUMO has been implicatedin the stabilization of target proteins and/or their localization to sub-cellular complexes.
Characteristics Synonyms: Sentrin-specific protease 2, Smt3ip2, Axam2, KIAA1331, Sentrin/SUMO-specific proteaseSENP2, SMT3-specific isopeptidase 2
Specificity This antibody is specific for SENP2. Species: Human, Mouse. Others not tested.

Application Details

Application Notes Western blot: 1/500 - 1/1000. Recommended Positive Control: Jurkat or NIH 3T3. A 60 kDa band is observed. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 0.5 mg/ml
Purification Purified
Buffer PBS containing 0.2% gelatin and 0.05% sodium azide
Storage Store the antibody at 2 - 8 °C up to six months or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing. Shelf life: one year from despatch.
Research Area Proteolysis / Ubiquitin
Restrictions For Research Use only

Publications

Kahyo, Nishida, Yasuda: "Involvement of PIAS1 in the sumoylation of tumor suppressor p53." in: Molecular cell, Vol. 8, Issue 3, pp. 713-8, 2001 (PubMed).

Alternatives

Alternatives for antigen "SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2)", type "Antibodies"
Hosts Rabbit (19), Mouse (7)
Reactivities Human (24), Mouse (Murine) (2), Rat (Rattus) (2)
Applications Western Blotting (WB) (25), ELISA (14), Immunohistochemistry (IHC) (7), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Flow Cytometry (FACS) (3), Immunofluorescence (IF) (2)
Epitopes C-Term (7), N-Term (3), AA 16-32 (1), Catalytic Domain (1), Internal Region (1), Middle Region (1)