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Antibodies
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anti-SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2) antibody
SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2) antibody
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN123434 |
| Quantity |
0.2 ml (0.5 mg/ml) (Variants) |
| Price |
319.00 $ Plus shipping costs $45.00
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| Shipping to |
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| Availability |
Will be delivered in 6 to 8 Business Days |
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Alternative name
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SENP2
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Gene ID
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59343
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UniProt
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Q9HC62
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Immunogen
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Synthetic peptide of human SENP2
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Cross-Reactivity
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Human, Mouse (Murine)
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Description
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Covalent attachment of one protein to another is one of the more prominentposttranslational modifications in respect to size and ubiquity. Ubiquitin is the mostfamiliar of the protein modifiers and its activation and transfer to target proteins has beenstudied extensively. Recently, a new group of ubiquitin-like proteins has been receiving alot of attention. SUMO, or Sentrin, is one of the most intriguing. SUMO has been implicatedin the stabilization of target proteins and/or their localization to sub-cellular complexes.
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Characteristics
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Synonyms: Sentrin-specific protease 2, Smt3ip2, Axam2, KIAA1331, Sentrin/SUMO-specific proteaseSENP2, SMT3-specific isopeptidase 2
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Specificity
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This antibody is specific for SENP2. Species: Human, Mouse. Others not tested.
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Application Notes
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Western blot: 1/500 - 1/1000. Recommended Positive Control: Jurkat or NIH 3T3. A 60 kDa band is observed. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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0.5 mg/ml
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Purification
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Purified
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Buffer
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PBS containing 0.2% gelatin and 0.05% sodium azide
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Storage
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Store the antibody at 2 - 8 °C up to six months or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing. Shelf life: one year from despatch.
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Research Area
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Proteolysis / Ubiquitin
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Restrictions
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For Research Use only
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Kahyo, Nishida, Yasuda: "Involvement of PIAS1 in the sumoylation of tumor suppressor p53." in: Molecular cell, Vol. 8, Issue 3, pp. 713-8, 2001 (PubMed).
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Alternatives for antigen "SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2)", type "Antibodies"
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Hosts
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Rabbit (19), Mouse (7)
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Reactivities
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Human (24), Mouse (Murine) (2), Rat (Rattus) (2)
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Applications
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Western Blotting (WB) (25), ELISA (14), Immunohistochemistry (IHC) (7), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Flow Cytometry (FACS) (3), Immunofluorescence (IF) (2)
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Epitopes
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C-Term (7), N-Term (3), AA 16-32 (1), Catalytic Domain (1), Internal Region (1), Middle Region (1)
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