Caspase 1 (CASP1) (AA 31-45) antibody

Details for Product No. ABIN123499
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Antigen
Epitope
AA 31-45
(33), (15), (8), (7), (7), (6), (6), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(176), (50), (42), (5), (4), (1), (1), (1), (1), (1)
Host
Rabbit
(184), (6), (5), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(12), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(165), (111), (77), (57), (15), (15), (14), (13), (12), (10), (5), (3), (2), (1)
Pubmed 4 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Discontinued
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Catalog No. ABIN123499
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Immunogen A synthetic peptide corresponding to amino acids 31-45 (QTRVLNKEEMEKVKR) of human caspase-1
Purification Protein G Chromatography
Alternative Name Caspase-1
UniProt P29466
Research Area Apoptosis/Necrosis
Application Notes Western blot (0.5 - 2 ug/ml) and immunohistochemistry on paraffim embeddeed sections. Optimal dilutions of this antibody are dependent on application and should be determined by the user. Formalin-fixed, paraffin-embedded section of human reactive lymph node stained for caspase-1 expression using SP7344 with a DAB chromogen and Hematoxylin counterstain. B is a higher magnification of A. Staining in macrophages is observed Western blot analysis of caspase-1 in HeLa cell lysate using ABIN123499 at 0.5 ug/ml.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.2% gelatin and 0.05% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 4°C for one month or in aliquots at –20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
anti-Caspase 1 (CASP1) (AA 31-45) antibody Western blot analysis of caspase-1 in HeLa cell lysate using ABIN123499 at 0.5 ug/ml.
anti-Caspase 1 (CASP1) (AA 31-45) antibody (2) Formalin-fixed, paraffin-embedded section of human reactive lymph node stained for caspase-1 expression using SP7344 with a DAB chromogen and Hematoxylin counterstain. B is a higher magnification of A. Staining in macrophages is observed
General Cerretti, Kozlosky, Mosley et al.: "Molecular cloning of the interleukin-1 beta converting enzyme." in: Science (New York, N.Y.), Vol. 256, Issue 5053, pp. 97-100, 1992 (PubMed).

Li, Allen, Banerjee et al.: "Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock." in: Cell, Vol. 80, Issue 3, pp. 401-11, 1995 (PubMed).

Yuan, Shaham, Ledoux et al.: "The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme." in: Cell, Vol. 75, Issue 4, pp. 641-52, 1993 (PubMed).

Tatsuta, Shiraishi, Mountz: "The prodomain of caspase-1 enhances Fas-mediated apoptosis through facilitation of caspase-8 activation." in: The Journal of biological chemistry, Vol. 275, Issue 19, pp. 14248-54, 2000 (PubMed).

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