anti-Caspase 1 antibody (CASP1) (AA 31-45)

Details for Product anti-CASP1 Antibody No. ABIN123499, Supplier: Login to see New
New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Alternatives
Epitope
AA 31-45
(37), (17), (16), (11), (10), (10), (8), (6), (5), (5), (5), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(239), (56), (37), (10), (4), (2), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(248), (17), (11), (2)
Clonality
Polyclonal
Conjugate
This Caspase 1 antibody is un-conjugated
(21), (14), (7), (2), (2), (2)
Application
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(218), (131), (112), (65), (23), (18), (16), (13), (6), (5), (3), (2)
Pubmed 4 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 0.1 mg
Shipping to United States ( )
Availability
Immunogen A synthetic peptide corresponding to amino acids 31-45 (QTRVLNKEEMEKVKR) of human caspase-1
Purification Protein G Chromatography
Alternative Name Caspase-1 (CASP1 Antibody Abstract)
UniProt P29466
Research Area Apoptosis/Necrosis
Pathways Apoptosis
Application Notes Western blot (0.5 - 2 ug/ml) and immunohistochemistry on paraffim embeddeed sections. Optimal dilutions of this antibody are dependent on application and should be determined by the user. Formalin-fixed, paraffin-embedded section of human reactive lymph node stained for caspase-1 expression using SP7344 with a DAB chromogen and Hematoxylin counterstain. B is a higher magnification of A. Staining in macrophages is observed Western blot analysis of caspase-1 in HeLa cell lysate using ABIN123499 at 0.5 ug/ml.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.2% gelatin and 0.05% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 4°C for one month or in aliquots at –20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Caspase 1 antibody (CASP1) (AA 31-45) (ABIN123499) Western blot analysis of caspase-1 in HeLa cell lysate using ABIN123499 at 0.5 ug/ml.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 1 antibody (CASP1) (AA 31-45) (ABIN123499) Formalin-fixed, paraffin-embedded section of human reactive lymph node stained for ca...
General Tatsuta, Shiraishi, Mountz: "The prodomain of caspase-1 enhances Fas-mediated apoptosis through facilitation of caspase-8 activation." in: The Journal of biological chemistry, Vol. 275, Issue 19, pp. 14248-54, 2000 (PubMed).

Yuan, Shaham, Ledoux et al.: "The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme." in: Cell, Vol. 75, Issue 4, pp. 641-52, 1993 (PubMed).

Li, Allen, Banerjee et al.: "Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock." in: Cell, Vol. 80, Issue 3, pp. 401-11, 1995 (PubMed).

Cerretti, Kozlosky, Mosley et al.: "Molecular cloning of the interleukin-1 beta converting enzyme." in: Science (New York, N.Y.), Vol. 256, Issue 5053, pp. 97-100, 1992 (PubMed).