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Structural Maintenance of Chromosomes 4 (SMC4) (AA 281-297) antibody

Details for Product No. ABIN123522
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Antigen
Epitope
AA 281-297
(4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Chicken, Human, Mouse (Murine), Rat (Rattus), Xenopus laevis
(33), (13), (13), (13), (13), (12), (11), (1), (1)
Host
Rabbit
(33), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(25), (9), (8), (3), (3), (2), (2), (1), (1), (1), (1)
Pubmed 2 references available
Quantity 0.1 mg
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Catalog No. ABIN123522
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Immunogen A synthetic peptide corresponding to amino acids 281-297 of human CAP-C
Purification Protein G chromatography
Alternative Name SMC4 / CAPC
Background The proteins belonging to structural maintenance of chromosomes (SMC) family play critical roles in chromosome structural changes. SMC proteins are involved in the proper condensation and segregation of mitotic chromosomes. Four human SMC proteins that form two distinct heterodimeric complexes in the cell, the human chromosome-associated protein (hCAP)-C and hCAP-E protein complex (hCAP-C/hCAP-E), and the human SMC1 (hSMC1) and hSMC3 protein complex (hSMC1/hSMC3) have been identified. Alternate Names: CAP-C.
UniProt Q9NTJ3
Application Notes Western blot analysis: 1-3 ug/ml. Recommended positive control: Ramos cell lysate. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.2% gelatin and 0.05% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
Supplier Images
anti-Structural Maintenance of Chromosomes 4 (SMC4) (AA 281-297) antibody Western blot analysis of CAP-C in Ramos cell lysate using ABIN123522 at 2 µg/ml.
General Schmiesing, Ball, Gregson et al.: "Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 22, pp. 12906-11, 1998 (PubMed).

Nishiwaki, Daigo, Kawasoe et al.: "Isolation and characterization of a human cDNA homologous to the Xenopus laevis XCAP-C gene belonging to the structural maintenance of chromosomes (SMC) family." in: Journal of human genetics, Vol. 44, Issue 3, pp. 197-202, 1999 (PubMed).

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