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Antibodies
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anti-Structural Maintenance of Chromosomes 4 (SMC4) antibody
Structural Maintenance of Chromosomes 4 (SMC4) antibody
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| Clonality |
Polyclonal |
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Host
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Reactivity
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 Alternatives Chicken, Human, Mouse (Murine), Rat (Rattus), Xenopus laevis
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Conjugate
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Application
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| Catalog no. |
ABIN123522 |
| Quantity |
0.1 mg (0.5 mg/ml) (Variants) |
| Price |
319.00 $ Plus shipping costs $45.00
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| Shipping to |
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| Availability |
Will be delivered in 6 to 8 Business Days |
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Alternative name
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SMC4 / CAPC
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UniProt
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Q9NTJ3
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Immunogen
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A synthetic peptide corresponding to amino acids 281-297 of human CAP-C
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Cross-Reactivity
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Chicken, Human, Mouse (Murine), Rat (Rattus), Xenopus laevis
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Description
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The proteins belonging to structural maintenance of chromosomes (SMC) family play critical roles in chromosome structural changes. SMC proteins are involved in the proper condensation and segregation of mitotic chromosomes. Four human SMC proteins that form two distinct heterodimeric complexes in the cell, the human chromosome-associated protein (hCAP)-C and hCAP-E protein complex (hCAP-C/hCAP-E), and the human SMC1 (hSMC1) and hSMC3 protein complex (hSMC1/hSMC3) have been identified. Alternate Names: CAP-C.
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Application Notes
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Western blot analysis: 1-3 ug/ml. Recommended positive control: Ramos cell lysate. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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0.5 mg/ml
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Purification
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Purified
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Buffer
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PBS containing 0.2% gelatin and 0.05% sodium azide
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Storage
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Store the antibody at 2 - 8 °C up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
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Restrictions
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For Research Use only
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Schmiesing, Ball, Gregson et al.: "Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 22, pp. 12906-11, 1998 (PubMed).
Nishiwaki, Daigo, Kawasoe et al.: "Isolation and characterization of a human cDNA homologous to the Xenopus laevis XCAP-C gene belonging to the structural maintenance of chromosomes (SMC) family." in: Journal of human genetics, Vol. 44, Issue 3, pp. 197-202, 1999 (PubMed).
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Alternatives for antigen "Structural Maintenance of Chromosomes 4 (SMC4)", type "Antibodies"
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Hosts
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Rabbit (37)
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Reactivities
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Human (35), Mouse (Murine) (20), Rat (Rattus) (20)
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Applications
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Western Blotting (WB) (21), Immunofluorescence (IF) (16), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), ELISA (4), Immunohistochemistry (IHC) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
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Conjugates
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Epitopes
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AA 281-297 (2), AA 47-61 (2), C-Term (2), N-Term (2), AA 1109-1127 (1), AA 493-504 (1), Internal Region (1)
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