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Structural Maintenance of Chromosomes 4 (SMC4) antibody

Antigen

Structural Maintenance of Chromosomes 4 (SMC4)
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Mouse (Murine), Rat (Rattus)
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB)
2 references available
Catalog no. ABIN123523
Quantity 0.1 mg  (0.5 mg/ml)  (Variants)
Price 330.00 $   Plus shipping costs $45.00
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anti-Structural Maintenance of Chromosomes 4 (SMC4) antibody

Additional Information
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Alternative name SMC4 / CAPC
UniProt Q9NTJ3
Immunogen A synthetic peptide corresponding amino acid residues 47-61 of human CAP-C
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Description The proteins belonging to structural maintenance of chromosomes (SMC) family play critical roles in chromosome structural changes. SMC proteins are involved in the proper condensation and segregation of mitotic chromosomes. Four human SMC proteins that form two distinct heterodimeric complexes in the cell, the human chromosome-associated protein (hCAP)-C and hCAP-E protein complex (hCAP-C/hCAP-E), and the human SMC1 (hSMC1) and hSMC3 protein complex (hSMC1/hSMC3) have been identified. Alternate Names: CAP-C.

Application Details
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Application Notes Western blot: 1.0 - 3.0 ug/ml. Recommended Positive Control: Ramos cell lysate. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 0.5 mg/ml
Purification Purified
Buffer PBS containing 0.2% gelatin and 0.05% sodium azide
Storage Store the antibody at 2 - 8 °C up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Restrictions For Research Use only

Publications
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Schmiesing, Ball, Gregson et al.: "Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 22, pp. 12906-11, 1998 (PubMed).

Nishiwaki, Daigo, Kawasoe et al.: "Isolation and characterization of a human cDNA homologous to the Xenopus laevis XCAP-C gene belonging to the structural maintenance of chromosomes (SMC) family." in: Journal of human genetics, Vol. 44, Issue 3, pp. 197-202, 1999 (PubMed).

Alternatives
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Alternatives for antigen "Structural Maintenance of Chromosomes 4 (SMC4)", type "Antibodies"
Hosts Rabbit (37)
Reactivities Human (35), Mouse (Murine) (20), Rat (Rattus) (20), Chicken (1), Xenopus laevis (1)
Applications Western Blotting (WB) (21), Immunofluorescence (IF) (16), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), ELISA (4), Immunohistochemistry (IHC) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (2), N-Term (2), AA 1109-1127 (1), AA 281-297 (1), AA 47-61 (1), AA 493-504 (1), Internal Region (1)