Inhibin, alpha (INHA) antibody

Antigen: Inhibin, alpha (INHA)

Synonyms: AW555078, MGC93593, INHA, MGC133965, si:dkey-91f15.2, MGC108500

Clonality: Monoclonal (R1)

Host: Mouse

Reactivity: Human

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN125231

Additional Information

Alternative name: Inhibin alpha

Immunogen: Synthetic peptide corresponding to the 1-32 amino terminal peptide of the alpha subunit of human inhibin.

Isotype: IgG2a  (Matching secondary antibodies)

Clone: R1

Specificity: Inhibin is a dimeric glycoprotein hormone from TGF-beta family made of alpha and beta subunits. This antibody recognizes the 32kD alpha subunit of human inhibin. Inhibin alpha is expressed in a wide variety of human tissues, such as brain, prostate, adrenal, granulose cells of ovary, sertoli cells of testis and in fetoplacental unit. This antibody cross reacts with human and weakly with cow and pig.

Application Details

Application Notes: Titer/Working Dilution: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Positive Control: Ovary. Cellular localization: Cytoplasmic Other Applications: Immunoprecipitation, Western blotting (1:100-500).

Concentration: 100ug/ml approximately

Buffer: This antibody is supplied as tissue culture supernatant containing sodium azide as preservative.

Storage: Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.

Research Area: Hormones

Restrictions: For Research Use. CE-certified for In Vitro Diagnostics (IVD) Use in the European Union

Publications

Publications: Groome, Hancock, Betteridge et al.: "Monoclonal and polyclonal antibodies reactive with the 1-32 amino terminal sequence of the alpha subunit of human 32K inhibin." in: Hybridoma, Vol. 9, Issue 1, pp. 31-42, 1990 (PubMed).

Costa, Ames, Walls et al.: "Inhibin immunohistochemistry applied to ovarian neoplasms: a novel, effective, diagnostic tool." in: Human pathology, Vol. 28, Issue 11, pp. 1247-54, 1997 (PubMed).