beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1) antibody

Antigen: beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1)

Synonyms: NK1, CD57, HNK1, LEU7, NK-1, GLCATP, GLCUATP, Hnk1, Glcatp, GlcAT-P, AI846286, KIAA4235, 0710007K08Rik, Hnk-1

Clonality: Monoclonal (NK1)

Host: Mouse

Reactivity: Human

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN125256

Additional Information

Alternative name: CD57

Immunogen: Human peripheral blood mononuclear cells.

Format: Supernatant (prediluted)

Isotype: IgM  (Matching secondary antibodies)

Clone: NK1

Specificity: This antibody is specific to a 110kD human CD57 myeloid associated glycoprotein. It stains mononuclear cells with natural killer activity, neuroendocrine cells and their tumors.

Application Details

Application Notes: Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Suitable for formalin/paraffin tissues. Positive Control: Tonsil. Cellular localization: Cell membrane

Concentration: 1 to 4 ug/ml

Buffer: This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections. No further titration is required.

Storage: Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.

Research Area: CD Antigens

Restrictions: For Research Use. CE-certified for In Vitro Diagnostics (IVD) Use in the European Union

Publications

Publications: McGarry, Helfand, Quarles et al.: "Recognition of myelin-associated glycoprotein by the monoclonal antibody HNK-1." in: Nature, Vol. 306, Issue 5941, pp. 376-8, 1984 (PubMed).

Lanier, Le, Phillips et al.: "Subpopulations of human natural killer cells defined by expression of the Leu-7 (HNK-1) and Leu-11 (NK-15) antigens." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 131, Issue 4, pp. 1789-96, 1983 (PubMed).

Abo, Balch: "A differentiation antigen of human NK and K cells identified by a monoclonal antibody (HNK-1)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 127, Issue 3, pp. 1024-9, 1981 (PubMed).