»
Antibodies
»
anti-Platelet-Derived Growth Factor AB/BB (PDGFAB/BB) antibody
Platelet-Derived Growth Factor AB/BB (PDGFAB/BB) antibody
| Antigen |
|
| Clonality |
Polyclonal |
|
Host
|
|
|
Reactivity
|
|
|
Application
|
 Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
|
| Catalog no. |
ABIN125318 |
| Quantity |
1ml (100ug/ml approximately) (Variants) |
| Price |
420.00 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 5 Business Days |
|
Alternative name
|
Platelet-Derived Growth Factor-AB/BB (PDGF-AB/BB)
|
|
Immunogen
|
A synthetic peptide derived from aa 101-116 of the human PDGF b chain.
|
|
Format
|
Ig-fraction
|
|
Specificity
|
Platelet-Derived Growth Factor (PDGF) is the major serum mitogen for cells of mesenchymal origin in humans. The biologically active protein is a dimmer composed of two related polypeptides designated A and B. The PDGF protein has been implicated both directly as well as indirectly in several pathological states including neoplasia, arthritis, arteriosclerosis and bone marrow sclerosis. This antibody is specific for /b form and reacts with PDGF (AB) and PDGF (BB) protein. This antibody cross reacts with rat.
|
|
Application Notes
|
Titer/Working Dilution: This antibody may be diluted to a titer of 1:50-1:100 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Angiosarcoma. Cellular localization: Cytoplasmic
|
|
Concentration
|
100ug/ml approximately
|
|
Buffer
|
Purified immunoglobulin fraction of rabbit antiserum against PDGF protein containing sodium azide as preservative.
|
|
Storage
|
Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.
|
|
Research Area
|
Growth Factors
|
|
Restrictions
|
For Research Use. CE-certified for In Vitro Diagnostics (IVD) Use in the European Union
|
Alternatives for antigen "Platelet-Derived Growth Factor AB/BB (PDGFAB/BB)", type "Antibodies"
