Proopiomelanocortin (POMC) antibody

Antigen: Proopiomelanocortin (POMC)

Synonyms: MSH, ACTH, pomc, SI:bZ36D5.1, SI:bZ36D5.4, si:bz36d5.2, POMC, LPH, NPP, POC, CLIP

Clonality: Monoclonal (AH26)

Host: Mouse

Reactivity: Human

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN125367

Additional Information

Alternative name: Adrenocorticotropic Hormone (ACTH)

Immunogen: BALB/C mice were injected with a synthetic peptide corresponding to amino acids 1-24 from the N-terminal of human ACTH.

Format: Supernatant

Isotype: IgG1  (Matching secondary antibodies)

Clone: AH26

Specificity: This antibody is specific to an epitope on the N-terminus of ACTH. This antibody stains corticotrophs in the adenohypophysis. It labels corticotrophs in adenohypophysis and is useful in the classification of pituitary adenomas.

Application Details

Application Notes: Titer/Working Dilution: This antibody may be diluted to a titer of 1:50-1:100 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Suitable for formalin/paraffin tissues. Positive Control: Pituitary. Cellular localization: Cytoplasmic

Concentration: 100ug/ml approximately

Buffer: This antibody is supplied as purified immunoglobulin fraction containing sodium azide as preservative.

Storage: Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.

Research Area: Hormones

Restrictions: For Research Use. CE-certified for In Vitro Diagnostics (IVD) Use in the European Union

Images

Formalin fixed paraffin embedded human pituitary stained with ACTH antibody