P63 antibody
| Antigen |
|
| Clonality |
Monoclonal (4A4) |
|
Host
|
|
|
Reactivity
|
|
|
Application
|
 Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
|
| Catalog no. |
ABIN125413 |
| Quantity |
500ul (100ug/ml approximately) (Variants) |
| Price |
272.00 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 5 Business Days |
|
Immunogen
|
A recombinant protein derived from amino acid 1-205 of human p63.
|
|
Format
|
Supernatant
|
|
Isotype
|
IgG2a kappa (Matching secondary antibodies)
|
|
Clone
|
4A4
|
|
Specificity
|
This antibody recognizes a 63 kD protein. The p63 gene is highly expressed in the basal or progenitor layers of many epithelial tissues. P63 shows remarkable structural similarity to p53 gene. Unlike p53, the p63 gene encodes multiple isotypes with remarkable divergent abilities to transactivate p53 reporter genes and induce apoptosis.
|
|
Application Notes
|
Titer/Working Dilution: This antibody may be diluted to a titer of 1:50 to 1:75 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Suitable for formalin/paraffin tissues. Positive Control: Skin. Cellular localization: Nuclear
|
|
Concentration
|
100ug/ml approximately
|
|
Buffer
|
This antibody is supplied as purified antibody containing sodium azide as preservative.
|
|
Storage
|
Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.
|
|
Research Area
|
Cancer, Signaling, Apoptosis/Necrosis
|
|
Restrictions
|
For Research Use. CE-certified for In Vitro Diagnostics (IVD) Use in the European Union
|
Alternatives for antigen "P63", type "Antibodies"
