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Ataxia Telangiectasia Mutated (ATM) antibody
| Antigen | Ataxia Telangiectasia Mutated (ATM) |
| Synonyms | AT1, ATA, ATC, ATD, ATE, ATDC, TEL1, TELO1, MGC74674, DKFZp781A0353, AI256621, C030026E19Rik, ATM, Tefu, atm/tefu, dATM, tef, DmelCG6535, CG6535, Xatm |
| Clonality | Monoclonal (ATX08) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Human, Mouse (Murine) |
| Application |
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
|
| Catalog no. | ABIN125439 |
| Quantity | 500ul (100ug/ml approximately) (Variants) |
| Price | 332.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 5 Business Days |
Additional Information
| Immunogen | BALB/C mice were injected with recombinant human ATM protein. |
| Format | Ig-fraction |
| Isotype | IgG1 (Matching secondary antibodies) |
| Clone | ATX08 |
| Specificity | This antibody reacts with a 350 kD protein known as ATM (Ataxia Telangiectasia Mutated). ATM protein phosphorylates p53 on serine 15 near the N terminus, thereby contributing to the activation and stabilization of p53 during the IR-induced DNA damage response. This antibody cross reacts with mouse. |
Application Details
| Application Notes | Titer/Working Dilution: This antibody may be diluted to a titer of 1:50-1:100 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the end user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Breast carcinoma. Cellular localization: Nuclear |
| Concentration | 100ug/ml approximately |
| Buffer | This antibody is supplied as purified immunoglobulin fraction containing sodium azide as preservative. |
| Storage | Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label. |
| Restrictions | For Research Use. CE-certified for In Vitro Diagnostics (IVD) Use in the European Union |
Alternatives
Alternatives for antigen "Ataxia Telangiectasia Mutated (ATM)", type "Antibodies"
| Hosts | Rabbit (58), Mouse (18), Goat (7), Sheep (2), Chicken (1) |
| Reactivities | Human (82), Mouse (Murine) (41), Rat (Rattus) (18), Hamster (2), Monkey (2) |
| Applications | Western Blotting (WB) (42), Immunofluorescence (IF) (28), Immunoprecipitation (IP) (20), Flow Cytometry (FACS) (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (15), Immunohistochemistry (IHC) (11), Enzyme Immunoassay (EIA) (10), ELISA (9), Dot Blot (Dot) (2), Immunocytochemistry (ICC) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1) |
| Conjugates | Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1) |
| Epitopes | pSer1981 (10), Ab-1981 (5), ppS1981 (1) |
