Matrix Metalloproteinase 10 (MMP10) antibody

Antigen: Matrix Metalloproteinase 10 (MMP10)

Synonyms: MMP-X1, MTMMP1, MT1-MMP, MMP18, RASI-1, SL-2, MMP-10, AV377895, MGC123370, MMP19

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN125610

Additional Information

Immunogen: A synthetic peptide from the hinge domain of human MMP-10.

Format: Ig-fraction, Purified

Specificity: This antibody reacts with a 57 kD protein (pro form) and 44 kD (active form) of MMP-10. Matrix metalloproteinase (MMPs) are a family of closely related zinc-containing proteolytic enzymes, capable of degrading connective tissue components. MMP-10 demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein and nonhelical region of collagen.

Application Details

Application Notes: Titer/Working Dilution: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions should be determined by the user. Suitable for formalin fixed paraffin tissue sections. No special pretreatment is required. Positive Control: Placenta. Cellular localization: Cytoplasmic

Concentration: 100ug/ml approximately

Buffer: Purified immunoglobulin fraction of rabbit antiserum against MMP-10 containing sodium azide as preservative.

Storage: Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.

Research Area: Extracellular Matrix

Restrictions: For Research Use. CE-certified for In Vitro Diagnostics (IVD) Use in the European Union