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Antibodies
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anti-Myeloid Cell Leukemia (Mcl-1) antibody
Myeloid Cell Leukemia (Mcl-1) antibody
| Antigen |
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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| Catalog no. |
ABIN125637 |
| Quantity |
500µl (100ug/ml approximately) (Variants) |
| Price |
281.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 Business Days |
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Immunogen
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A synthetic peptide corresponding to aa 121-139 of human MCl-1.
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Format
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Ig-fraction, Purified
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Specificity
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This antibody reacts with a 42 kD protein. Myeloid cell leukemia-1 (MCL-1) is a member of the bcl-2 family. The carboxy terminal of Mcl-1 and bcl-2 share significant sequence homology. Expression of Mcl-1 is increased upon exposure of ML-1 cells to various types of DNA damaging agents, along with increases in GADD45 and Bax and a decrease in bcl-2.
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Application Notes
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Titer/Working Dilution: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Positive Control: Tonsil. Cellular localization: Cytoplasmic, nuclear Other Applications: Immunoprecipitation, Western blotting (1:100-500).
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Concentration
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100ug/ml approximately
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Buffer
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Purified immunoglobulin fraction of rabbit antiserum against MCL-1 containing sodium azide as preservative.
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Storage
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Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.
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Research Area
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Cancer
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Restrictions
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For Research Use. CE-certified for In Vitro Diagnostics (IVD) Use in the European Union
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Alternatives for antigen "Myeloid Cell Leukemia (Mcl-1)", type "Antibodies"
