Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1) antibody

Antigen: Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1)

Synonyms: Glut1, Glut-1, GTG1, Gtg3, GLUTB, RATGTG1, GLUT-1, GLUT1, SLC2A1, Dmglut1, GLU, glut1, DmelCG1086, CG1086, GLT1, GLUCOSE TRANSPORTER 1, PGLCT, PLASTIDIC GLC TRANSLOCATOR, T21H19.70, T21H19_70, DKFZp459K0913, PED, GLUT, DYT17, DYT18, MGC141895, MGC141896

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat (Rattus)

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN125643

Additional Information

Alternative name: Glucose Transporter 1 (Glut 1)

Immunogen: A synthetic peptide derived from c-terminal of human GLUT-1.

Format: Ig-fraction, Purified

Specificity: This antibody reacts with a 55 kD protein. Glucose is fundamental to the metabolism of mammalian cells. Several glucose transporter protein (Glut) isoforms have been identified and shown to function in response in insulin and IGF-1 induced signaling. GLUT-1 is detectable in many human tissues including those of the colon, lung, stomach, esophagus and breast. GLUT-1 immunoreactivity in some cancers, including trans carcinoma of the urinary bladder has been associated with aggressive behavior. This antibody crossreacts with rat.

Synonyms: Glut1, Glut-1, GTG1, Gtg3, GLUTB, RATGTG1, GLUT-1, GLUT1, SLC2A1, Dmglut1, GLU, glut1, DmelCG1086, CG1086, GLT1, GLUCOSE TRANSPORTER 1, PGLCT, PLASTIDIC GLC TRANSLOCATOR, T21H19.70, T21H19_70, DKFZp459K0913, PED, GLUT, DYT17, DYT18, MGC141895, MGC141896

Application Details

Application Notes: Titer/Working Dilution: This antibody may be diluted to a titer of 1:50-1:100 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Breast carcinoma. Cellular localization: Cytoplasmic

Concentration: 100ug/ml approximately

Buffer: Purified immunoglobulin fraction of rabbit antiserum against GLUT-1 containing sodium azide as preservative.

Storage: Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.

Research Area: Metabolism, Transporters, Diabetes

Restrictions: For Research Use. CE-certified for In Vitro Diagnostics (IVD) Use in the European Union

Images

Formalin fixed paraffin embedded human esophagus stained with GLUT-1 antibody