Insulin (INS) antibody
| Antigen |
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| Synonyms |
ILPR, IRDN, INS, MGC159719, ins1, xins, ins1-a, Insulin |
| Clonality |
Monoclonal (IN-05) |
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Host
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Reactivity
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Human (159), Pig (Porcine) (91), Rat (Rattus) (59), Mouse (Murine) (45), Cow (Bovine) (40), Rabbit (29), Horse (Equine) (22), Dog (Canine) (9), Chicken (3), Guinea Pig (3), Sheep (Ovine) (3), Cat (Feline) (2)
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Application
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 Alternatives Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Radioimmunoassay (RIA), Immunocytochemistry (ICC)
Immunofluorescence (IF) (77), Flow Cytometry (FACS) (71), ELISA (50), Enzyme Immunoassay (EIA) (34), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (34), Western Blotting (WB) (25), Radioimmunoassay (RIA) (24), Immunohistochemistry (Frozen Sections) (IHC (fro)) (21), Immunohistochemistry (IHC) (17), Immunoprecipitation (IP) (13), ELISA (Capture) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (6), Functional Studies (Func) (3), Immunocytochemistry (ICC) (3), Immunoelectron Microscopy (IEM) (3)
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| Catalog no. |
ABIN125702 |
| Quantity |
0.1 mg (1 mg/ml) (Variants) |
| Price |
260.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 3 to 5 Business Days |
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Alternative name
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Insulin
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Immunogen
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Porcine insulin.
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Format
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Azide Free
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Isotype
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IgG1 (Matching secondary antibodies)
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Clone
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IN-05
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Description
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Insulin and glucagon are pancreatic endocrine hormones secreted by islet cells within thepancreas. The stimulus for insulin secretion is a HIGH blood glucose. Deficiency of insulinresults in diabetes mellitus, one of the leading causes of morbidity and mortality in thegeneral population.
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Specificity
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The antibody IN-05 reacts with insulin, one of the major regulatory endocrine hormones ofintermediate metabolism, normally secreted by the beta cells (a type of islet cells) of thepancreas, it is also present in tumors of B cell origin such as insulinoma.
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Application Notes
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Functional Application: The antibody IN-05 blocks binding of insulin to the receptor.
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Concentration
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1 mg/ml
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Purity
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> 95% (by SDS-PAGE)
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Purification
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Purified from ascites by protein-A affinity chromatography.
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Buffer
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Azide free phosphate buffered saline (PBS), approx. pH 7.4, 0.2 ยต m filter sterilized.
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Storage
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Store at 2-8 o C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20 o C. Avoid freeze/thaw cycles.
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Research Area
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Neurology, Diabetes, Hormones
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Restrictions
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For Research Use only
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Alternatives for antigen "Insulin (INS)", type "Antibodies"
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Hosts
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Rabbit (89), Mouse (82), Guinea Pig (8), Sheep (4), Chicken (1)
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Reactivities
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Human (159), Pig (Porcine) (91), Rat (Rattus) (59), Mouse (Murine) (45), Cow (Bovine) (40), Rabbit (29), Horse (Equine) (22), Dog (Canine) (9), Chicken (3), Guinea Pig (3), Sheep (Ovine) (3), Cat (Feline) (2)
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Applications
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Immunofluorescence (IF) (77), Flow Cytometry (FACS) (71), ELISA (50), Enzyme Immunoassay (EIA) (34), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (34), Western Blotting (WB) (25), Radioimmunoassay (RIA) (24), Immunohistochemistry (Frozen Sections) (IHC (fro)) (21), Immunohistochemistry (IHC) (17), Immunoprecipitation (IP) (13), ELISA (Capture) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (6), Functional Studies (Func) (3), Immunocytochemistry (ICC) (3), Immunoelectron Microscopy (IEM) (3)
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Conjugates
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Alexa Fluor 350 (6), Alexa Fluor 488 (6), Alexa Fluor 555 (6), Alexa Fluor 647 (6), Biotin (6), PE,Cy5.5 (6), HRP (5), FITC (4), Alexa Flour 488 (3), Cy3 (3), Cy5 (3), Cy5.5 (3), Cy7 (3), Gold (3), PE (3), PE,Cy3 (3), PE,Cy5 (3), PE,Cy7 (3), RBITC (3)
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Epitopes
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beta chain (3), AA 57-87 (2), C-Term (2), Center (1)
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