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Keratin 2 (KRT2) (AA 2-23), (N-Term) antibody

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Synonyms KRT2, krt2a, CK-2e, K2e, KRT2A, KRT2E, KRTE, BB005427, Krt2-17, Krt2-2, Krt2e, Kb2, K2E
N-Term, AA 2-23
(9), (7), (7), (7), (6), (3), (2), (1), (1), (1), (1)
(35), (19), (9), (4), (3), (1), (1)
(35), (15), (3)
Clonality (Clone)
Monoclonal ()
(5), (3)
Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(42), (23), (18), (17), (15), (8), (7), (2), (2), (1), (1), (1)
Pubmed 2 references available
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Quantity 1 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Synthetic peptide (N-terminal amino acids Nos. 2-23) of human keratin K2 (MW 65,852).
Clone Ks 2-398-3-1
Isotype IgG1
Purification Supernatant
Alternative Name Cytokeratin 2e (KRT2 Antibody Abstract)
Background Keratins are the major gene product of keratinocytes and form the intermediate filament cytoskeletal network in these cells. In cells of the upper spinous layer, KRT2E and KRT9 are expressed. Although the expression of KRT9 is limited to palmoplantar epidermis, KRT2E is expressed not only in this tissue but also in other regions, notably the epidermis covering the knee, thigh, and groin. It is not known whether these keratins simply replace their respective type I or type II counterpart in the preexisting KRT1/KRT10 network or dimerize with another, as yet undiscovered keratin partner.Synonyms: CK2e, Cytokeratin-2e, K2e, KRT2, KRT2A, KRT2E, Keratin, Keratin-2, type II cytoskeletal 2 epidermal
Gene ID 9606
UniProt P35908
Research Area Extracellular Matrix
Application Notes Immunoblotting. Immunohistochemistry: 1: 150.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.
Background publications Swensson, Langbein, McMillan et al.: "Specialized keratin expression pattern in human ridged skin as an adaptation to high physical stress." in: The British journal of dermatology, Vol. 139, Issue 5, pp. 767-75, 1999 (PubMed).

Collin, Moll, Kubicka et al.: "Characterization of human cytokeratin 2, an epidermal cytoskeletal protein synthesized late during differentiation." in: Experimental cell research, Vol. 202, Issue 1, pp. 132-41, 1992 (PubMed).

Catalog No. ABIN125984
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