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Keratin 8 (KRT8) antibody (Biotin)

Antigen

Keratin 8 (KRT8)
Synonyms
K8, KO, CK8, CYK8, K2C8, CARD2, Card2, EndoA, Krt2-8, Krt-2.8, AA960620, AL022697, AU019895, MGC118110, CYKER, KRT2-8, krt8, MGC53564, KRT8, ck8, cyk8, k2c8, card2, krt2-5, MGC69490, cb59, zf-K8, MGC7 ... show more
Clonality Monoclonal (Ks8-7)
Host
Alternatives

Mouse
Reactivity
Alternatives

Hamster, Human, Mouse (Murine), Rat (Rattus)
Conjugate
Alternatives Biotin
Application
Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
4 references available
Catalog no. ABIN125991
Quantity 0.25 mL
Price 495.00 $   Plus shipping costs $45.00
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Additional Information
Application Details Publications Alternatives back to top

Alternative name Cytokeratin 8
UniProt P05787
Immunogen Cytoskeletal proteins from cultured HeLa cells
Cross-Reactivity Hamster, Human, Mouse (Murine), Rat (Rattus)
Isotype IgG1
Clone Ks8-7
Description Cytokeratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins andexists in combination with cytokeratin 18. Cytokeratin 8 is primarily found in the nonsquamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by theuse of antibodies that recognize only cytokeratin polypeptides 8 and 18.
Characteristics Synonyms: KRT8, CYK8, Cytokeratin-8, CK8, Keratin-8, K8, Cytokeratin endo A, Keratin, type IIcytoskeletal 8
Synonyms K8, KO, CK8, CYK8, K2C8, CARD2, Card2, EndoA, Krt2-8, Krt-2.8, AA960620, AL022697, AU019895, MGC118110, CYKER, KRT2-8, krt8, MGC53564, KRT8, ck8, cyk8, k2c8, card2, krt2-5, MGC69490, cb59, zf-K8, MGC76893, wu:fa91a11, wu:fd19e09, wu:fl23c09, etID20321.6, zfk8, DreK8, cb186, krt2-8, MGC85764, sb:cb186, MGC174782, wu:fa20h05, wu:fa95h10, wu:fb96c06, DKFZp468F2127

Application Details
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Application Notes Western Blot. Immunocytology. Immunohistochemistry (1: 10) on frozen tissues and paraffin-embedded sections aftermicrowave treatment. Incubation time: 1 h at RT. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Storage Store the antibody undiluted at 2-8°C. Shelf life: one year from despatch.
Research Area Cancer, Cytoskeleton, Cytokeratins, Extracellular Matrix
Restrictions For Research Use only

Publications
Application Details Alternatives back to top

Bártek, Vojtĕsek, Stasková et al.: "A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology." in: The Journal of pathology, Vol. 164, Issue 3, pp. 215-24, 1991 (PubMed).

Moll, Franke, Schiller et al.: "The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells." in: Cell, Vol. 31, Issue 1, pp. 11-24, 1983 (PubMed).

Gomi, Yokoyama, Fujimoto et al.: "Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions." in: Neuron, Vol. 14, Issue 1, pp. 29-41, 1995 (PubMed).

Stumptner, Fuchsbichler, Heid et al.: "Mallory body--a disease-associated type of sequestosome." in: Hepatology (Baltimore, Md.), Vol. 35, Issue 5, pp. 1053-62, 2002 (PubMed).

Alternatives
Application Details Publications back to top

Alternatives for antigen "Keratin 8 (KRT8)", type "Antibodies"
Hosts Rabbit (126), Mouse (117), Guinea Pig (3), Chicken (2), Goat (1)
Reactivities Human (230), Mouse (Murine) (74), Rat (Rattus) (65), Pig (Porcine) (29), Dog (Canine) (21), Chicken (20), Cow (Bovine) (13), Sheep (Ovine) (9), Rabbit (6), Zebrafish (Danio rerio) (5), Hamster (3), Xenopus laevis (3), Cat (Feline) (1), Mammalian (1), Monkey (1)
Applications Western Blotting (WB) (153), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (113), Immunofluorescence (IF) (80), Immunohistochemistry (IHC) (63), ELISA (59), Immunocytochemistry (ICC) (49), Immunoprecipitation (IP) (34), Immunohistochemistry (Frozen Sections) (IHC (fro)) (26), Immunohistochemistry (Fixed) (IHC (fx)) (18), Flow Cytometry (FACS) (14), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (8), Immunoelectron Microscopy (IEM) (2), To be determined by user (TBD) (1)
Conjugates Biotin (11), FITC (4), HRP (3), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2)
Epitopes N-Term (23), pSer23 (19), C-Term (7), pSer74 (7), Internal Region (5), AA 91-381 (4), pSer73 (4), AA 391-483 (3), pSer74,Internal Region (3), AA 1-483 (2), Ser74 (2), pSer431 (2), AA 353-367 (1), AA 450-477 (1), Center (1), Internal Region,AA 286-315 (1), Ser73 (1), pSer432 (1)